Immunoglobulin light chains activate nuclear factor-κB in renal epithelial cells through a Src-dependent mechanism.
about
Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion.Receptor-associated protein blocks internalization and cytotoxicity of myeloma light chain in cultured human proximal tubular cells.C-src enriched serum microvesicles are generated in malignant plasma cell dyscrasia.Improvement in renal function and its impact on survival in patients with newly diagnosed multiple myeloma.Serum free light chains and the risk of ESRD and death in CKDThe pathogenesis and diagnosis of acute kidney injury in multiple myeloma.Early Application of High Cut-Off Haemodialysis for de-Novo Myeloma Nephropathy is Associated with Long-Term Dialysis-Independency and Renal Recovery.Prooxidant-induced c-Src/nuclear factor kappa B-coupled signalling in sensory ganglia mediates cutaneous hyperalgesia.Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi SyndromeLong-term reversibility of renal dysfunction associated to light chain deposition disease with bortezomib and dexamethasone and high dose therapy and autologous stem cell transplantation.Management of myeloma-associated renal dysfunction in the era of novel therapies.Novel approaches for reducing free light chains in patients with myeloma kidney.Proteinuria and progression of glomerular diseases.Current treatments for renal failure due to multiple myeloma.A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformationDeficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-κB and inhibition of monocyte chemoattractant protein-1 in urethane-induced lung tumor model.Managing renal complications in multiple myeloma.Current treatments for renal failure due to multiple myeloma.Treating myeloma cast nephropathy without treating myeloma.Pivotal role of apoptosis signal-regulating kinase 1 in monoclonal free light chain-mediated apoptosis.Immunoglobulin Free Light Chains and GAGs Mediate Multiple Myeloma Extracellular Vesicles Uptake and Secondary NfκB Nuclear Translocation.Contribution of polyclonal free light chain deposition to tubular injury.Paraprotein-Related Kidney Disease: Evaluation and Treatment of Myeloma Cast Nephropathy.Bortezomib overcomes the negative prognostic impact of renal impairment in a newly diagnosed elderly patient with multiple myeloma: A case report.Bortezomib-based therapy combined with high cut-off hemodialysis is highly effective in newly diagnosed multiple myeloma patients with severe renal impairment.Hematologic and renal improvement of monoclonal immunoglobulin deposition disease after treatment with bortezomib-based regimens.The role of novel agents on the reversibility of renal impairment in newly diagnosed symptomatic patients with multiple myeloma
P2860
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P2860
Immunoglobulin light chains activate nuclear factor-κB in renal epithelial cells through a Src-dependent mechanism.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@ast
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@en
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@nl
type
label
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@ast
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@en
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@nl
prefLabel
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@ast
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@en
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@nl
P2093
P2860
P1433
P1476
Immunoglobulin light chains ac ...... ugh a Src-dependent mechanism.
@en
P2093
Kolitha Basnayake
Kristal J Aaron
Paul W Sanders
Pei-Xuan Wang
Wei-Zhong Ying
P2860
P304
P356
10.1182/BLOOD-2010-08-302505
P407
P577
2010-11-22T00:00:00Z