The GSK3 beta signaling cascade and neurodegenerative disease.
about
GSK-3 phosphorylates delta-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysisA novel mass spectrometry-based assay for GSK-3beta activity.(-)-SCR1693 Protects against Memory Impairment and Hippocampal Damage in a Chronic Cerebral Hypoperfusion Rat ModelDown-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's diseaseGlycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1GSK3beta in ethanol neurotoxicityThe role of GSK3beta in the development of the central nervous systemMorphine enhances HIV-1SF162-mediated neuron death and delays recovery of injured neuritesMagnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer's modelPS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutationsHuman neural stem cells alleviate Alzheimer-like pathology in a mouse model.Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.Activation of PI3-K/Akt pathway for thermal preconditioning to protect cultured cerebellar granule neurons against low potassium-induced apoptosis.The COMT Val158 Met polymorphism as an associated risk factor for Alzheimer disease and mild cognitive impairment in APOE 4 carriersUp-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin.Huntington's disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads databaseConcerted perturbation observed in a hub network in Alzheimer's diseaseEndogenous repair by the activation of cell survival signalling cascades during the early stages of rat Parkinsonism.Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling.Overexpression of glycogen synthase kinase 3beta sensitizes neuronal cells to ethanol toxicityActivation of GSK-3β and caspase-3 occurs in Nigral dopamine neurons during the development of apoptosis activated by a striatal injection of 6-hydroxydopamineSignalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.Decreased store operated Ca2+ entry in dendritic cells isolated from mice expressing PKB/SGK-resistant GSK3.Cell signaling underlying epileptic behavior.GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder.Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?A model for dynamic regulation of choline acetyltransferase by phosphorylation.Molecular targets of opiate drug abuse in neuroAIDS.Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain.IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo.Disease-associated mutations inactivate AMP-lysine hydrolase activity of Aprataxin.Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementiasActivity-dependent regulation of dendritic growth and maintenance by glycogen synthase kinase 3βPhosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis.Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.Insulin receptor signaling in the development of neuronal structure and function.Histamine pharmacology and new CNS drug targets.Reelin signaling in development, maintenance, and plasticity of neural networksThe MEF2 family and the brain: from molecules to memory.
P2860
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P2860
The GSK3 beta signaling cascade and neurodegenerative disease.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The GSK3 beta signaling cascade and neurodegenerative disease.
@ast
The GSK3 beta signaling cascade and neurodegenerative disease.
@en
The GSK3 beta signaling cascade and neurodegenerative disease.
@nl
type
label
The GSK3 beta signaling cascade and neurodegenerative disease.
@ast
The GSK3 beta signaling cascade and neurodegenerative disease.
@en
The GSK3 beta signaling cascade and neurodegenerative disease.
@nl
prefLabel
The GSK3 beta signaling cascade and neurodegenerative disease.
@ast
The GSK3 beta signaling cascade and neurodegenerative disease.
@en
The GSK3 beta signaling cascade and neurodegenerative disease.
@nl
P1476
The GSK3 beta signaling cascade and neurodegenerative disease
@en
P2093
Michael D Kaytor
P304
P356
10.1016/S0959-4388(02)00320-3
P50
P577
2002-06-01T00:00:00Z