High-resolution interrogation of functional elements in the noncoding genome - Wikidata - awgldk - TriplyDB

High-resolution interrogation of functional elements in the noncoding genome

High-resolution interrogation of functional elements in the noncoding genome

http://www.wikidata.org/entity/Q34679064

about

Genome engineering of stem cell organoids for disease modeling.Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening Functional interrogation of non-coding DNA through CRISPR genome editing.CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease.Capturing genomic relationships that matter Recent advances in high-throughput approaches to dissect enhancer function CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments.A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells.Three-dimensional genome architecture and emerging technologies: looping in disease.Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.Human gene essentiality.CRISPR-Cas9-mediated functional dissection of 3'-UTRs.Making the cut in the dark genome.The Future of CRISPR Applications in the Lab, the Clinic and Society.ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis.Functional assessment of human enhancer activities using whole-genome STARR-sequencing.Principles for the regulation of multiple developmental pathways by a versatile transcriptional factor, BLIMP1.CRISPR-based strategies for studying regulatory elements and chromatin structure in mammalian gene control.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.Genome Engineering for Personalized Arthritis Therapeutics.Towards CRISPR/Cas crops - bringing together genomics and genome editing.Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.CRISPR/Cas9-mediated noncoding RNA editing in human cancers.Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches.Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer-promoter contacts.The role of long noncoding RNAs in cancer: the dark matter matters.CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions.The dark side of the human genome.Deep learning in pharmacogenomics: from gene regulation to patient stratification.Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation.CRISPR-based methods for high-throughput annotation of regulatory DNA.Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease.The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes.Reversal of Resistance in Targeted Therapy of Metastatic Melanoma: Lessons Learned from Vemurafenib (BRAFV600E-Specific Inhibitor).CRISPR-based reagents to study the influence of the epigenome on gene expression

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High-resolution interrogation of functional elements in the noncoding genome

http://www.wikidata.org/entity/Q34679064

description

2016 nî lūn-bûn

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2016 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

High-resolution interrogation of functional elements in the noncoding genome

@ast

High-resolution interrogation of functional elements in the noncoding genome

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High-resolution interrogation of functional elements in the noncoding genome

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type

label

High-resolution interrogation of functional elements in the noncoding genome

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High-resolution interrogation of functional elements in the noncoding genome

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High-resolution interrogation of functional elements in the noncoding genome

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prefLabel

High-resolution interrogation of functional elements in the noncoding genome

@ast

High-resolution interrogation of functional elements in the noncoding genome

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High-resolution interrogation of functional elements in the noncoding genome

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High-resolution interrogation of functional elements in the noncoding genome

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Christine Cheng

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Feng Zhang

http://www.w3.org/2001/XMLSchema#string

Jason Wright

http://www.w3.org/2001/XMLSchema#string

Julia Joung

http://www.w3.org/2001/XMLSchema#string

Kaijie Zheng

http://www.w3.org/2001/XMLSchema#string

Neville E Sanjana

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Ophir Shalem

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Pierre Fontanillas

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

An integrated encyclopedia of DNA elements in the human genome

Genomic views of distant-acting enhancers

Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Capturing chromosome conformation

A Hidden Markov Model approach to variation among sites in rate of evolution

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