Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro. - Wikidata - awgldk - TriplyDB

Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.

Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.

http://www.wikidata.org/entity/Q34679899

about

Mechanisms of islet amyloidosis toxicity in type 2 diabetes Molecular mechanisms of diabetic retinopathy, general preventive strategies, and novel therapeutic targets A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation Sporothrix schenckii complex and sporotrichosis, an emerging health problem.Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.Amyloid formation in heterogeneous environments: islet amyloid polypeptide glycosaminoglycan interactions Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis.Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology.Localized amyloids important in diseases outside the brain--lessons from the islets of Langerhans and the thoracic aorta.Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis.Apoptosis Repressor with Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation.Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis.Drug-Mediated Regulation of Glycosaminoglycan Biosynthesis.A visualizable chain-terminating inhibitor of glycosaminoglycan biosynthesis in developing zebrafish.A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc.Nanoparticle-Cell Interaction: A Cell Mechanics Perspective.Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets.

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P2860

Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.

http://www.wikidata.org/entity/Q34679899

description

2007 nî lūn-bûn

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2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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type

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

@ast

Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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AJPCELL.00208.2007

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American Journal of Physiology - Cell Physiology

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Inhibition of glycosaminoglyca ...... et amyloid formation in vitro.

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P2093

Jayalakshmi Udayasankar

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Rebecca L Hull

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Robert Kisilevsky

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Sakeneh Zraika

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Thomas N Wight

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Walter A Szarek

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P2860

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.

In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis

Basement membrane proteoglycans: from cellar to ceiling.

Inhibition of amyloid A amyloidogenesis in vivo and in tissue culture by 4-deoxy analogues of peracetylated 2-acetamido-2-deoxy-alpha- and beta-d-glucose: implications for the treatment of various amyloidoses.

Glucose- and time-dependence of islet amyloid formation in vitro.

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C1586-93

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10.1152/AJPCELL.00208.2007

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