Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
about
Targeting LKB1 in cancer - exposing and exploiting vulnerabilitiesTo breathe or not to breathe: the haematopoietic stem/progenitor cells dilemmaHypoxia and metabolic properties of hematopoietic stem cellsMitophagy in hematopoietic stem cells: the case for explorationNutrient-sensing pathways and metabolic regulation in stem cellsGSK-3 as potential target for therapeutic intervention in cancerMolecular mechanism of extrinsic factors affecting anti-aging of stem cellsTAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanismsSMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planariansThe emerging role of AMPK in the regulation of breathing and oxygen supplyThe protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathwayLncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stressChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte developmentNotchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cellsGene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte developmentAberrant intestinal stem cell lineage dynamics in Peutz-Jeghers syndrome and familial adenomatous polyposis consistent with protracted clonal evolution in the cryptNew Roles of Lkb1 in Regulating Adipose Tissue Development and Thermogenesis.Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemiaMetabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicityMetabolic profiles of biological aging in American Indians: the Strong Heart Family StudyLiver kinase B1 regulates the centrosome via PLK1.PAR-4/LKB1 regulates DNA replication during asynchronous division of the early C. elegans embryo.Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1.The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance.Metabolic requirements for the maintenance of self-renewing stem cells.Developmental enhancement of adenylate kinase-AMPK metabolic signaling axis supports stem cell cardiac differentiation.Signal transduction by mitochondrial oxidants.Metabolic regulation of redox status in stem cells.The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cellsThe autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.AMPK at the nexus of energetics and aging.LKB1 preserves genome integrity by stimulating BRCA1 expression.Role of reactive oxygen species in the radiation response of human hematopoietic stem/progenitor cells.Stem cells and the impact of ROS signaling.Liver kinase B1 suppresses lipopolysaccharide-induced nuclear factor κB (NF-κB) activation in macrophages
P2860
Q26801412-04FEA0ED-D158-42F0-B5F2-850E06CD193AQ26825809-1CB31BEE-7B15-4C62-9F66-47EC150EBB7CQ26853702-C7C3656D-CFD9-446E-BA99-6A4B5C291507Q26865108-077D4BF5-32D4-4FB4-BFE5-830A784F6BC0Q27011433-024E8E6D-C184-43C9-935D-8540EA2CCA71Q27013811-694AA227-65D0-41ED-A616-86F7D25F7E8BQ27021113-3C6A86B8-FB88-4358-8F51-BD15A0BC0525Q27332368-56BD0CF8-E153-4FD9-8D77-73CE11F6D6CFQ27334311-D3FA8FCD-8503-4F42-8E54-BD0BF3BDE699Q28072485-A09ECF3D-8BE0-4455-B36C-FD4A48B671AFQ28117215-142154C5-A23B-4117-B230-46332787C82CQ28274325-DCC8028E-41BF-4F6F-9469-80C121127B2EQ28383732-C9CFFB34-9FC2-43A6-96D0-2EC897601D71Q28507620-0418925C-91E3-40C2-A86F-C340B3AA2274Q28513787-FB638BB0-E96D-4465-9514-4FF26F0903B1Q28590221-E801C6E5-1F3C-4FC4-88A1-663D78CA7205Q28709232-0A500818-2ACE-4BAC-B724-E10E5D5C09BBQ30244650-CEABD657-1B55-433A-82C5-8688F1FB5694Q30608477-992155CF-937C-45CC-A7F1-4D813EE26FA4Q30656970-693A29FB-F183-46D4-BEFC-8BFF210E2339Q33551834-E7853502-B4A2-4977-9BE0-3A3616EB39F9Q33577707-8FA27915-8148-4C7B-951C-324E69E34F49Q33654208-AFB8AF8D-5FAC-4A8B-98F8-3DE32530902DQ33663198-7835BBB4-6B51-474D-BD0A-6CE5677BFC79Q33685458-2A5860AB-E214-44D5-BA70-C0ADA281507DQ33852075-5570F426-60AD-4286-AD69-505C0BE7D38AQ33893346-98E36619-A279-4DBF-8E03-571A58CA50E3Q33893826-0BD4022D-BFDB-448A-8A11-39C166EDD4CEQ34207242-D0F11281-C3F4-4981-B7D2-94694BBBAEA0Q34240794-B330D3F5-C109-4144-92E0-C697D9AD738DQ34568200-2D1F4644-8EDC-4B51-A8C4-A95F8B59FD85Q34570776-7C1BF11D-4787-49AC-ABAD-B8ED4A8AC66EQ34647637-1EA49097-5627-4844-9243-224ABD2215B7Q34681351-40D600B1-4316-4D34-B99A-ED6E486B9695Q34693980-82707917-AA5C-4CB0-868F-5D54C490B607Q34871517-E3397E6E-9B81-42F2-ACCF-6C38611D8F7FQ34883396-A2713E97-0E71-4755-AA01-CDD2802887B7Q34923051-7FAA5151-D151-4841-85D3-4285F18FB9E5Q34999296-A0CA70D1-39E2-4E4C-AE78-7DEDA19F25E7Q35002962-0A9DA09E-B404-418D-B6F7-C470B35DF745
P2860
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@ast
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@en
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@nl
type
label
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@ast
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@en
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@nl
prefLabel
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@ast
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@en
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@nl
P2093
P2860
P356
P1433
P1476
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.
@en
P2093
Eliot Fletcher-Sananikone
Ergün Sahin
Ronald A Depinho
Shan Jiang
Simona Colla
Y Alan Wang
Yingchun Liu
P2860
P2888
P304
P356
10.1038/NATURE09595
P407
P50
P577
2010-12-01T00:00:00Z
P5875
P6179
1037784061