Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. - Wikidata - awgldk - TriplyDB

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

http://www.wikidata.org/entity/Q34679984

about

Targeting LKB1 in cancer - exposing and exploiting vulnerabilities To breathe or not to breathe: the haematopoietic stem/progenitor cells dilemma Hypoxia and metabolic properties of hematopoietic stem cells Mitophagy in hematopoietic stem cells: the case for exploration Nutrient-sensing pathways and metabolic regulation in stem cells GSK-3 as potential target for therapeutic intervention in cancer Molecular mechanism of extrinsic factors affecting anti-aging of stem cells TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians The emerging role of AMPK in the regulation of breathing and oxygen supply The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development Aberrant intestinal stem cell lineage dynamics in Peutz-Jeghers syndrome and familial adenomatous polyposis consistent with protracted clonal evolution in the crypt New Roles of Lkb1 in Regulating Adipose Tissue Development and Thermogenesis.Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity Metabolic profiles of biological aging in American Indians: the Strong Heart Family Study Liver kinase B1 regulates the centrosome via PLK1.PAR-4/LKB1 regulates DNA replication during asynchronous division of the early C. elegans embryo.Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1.The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance.Metabolic requirements for the maintenance of self-renewing stem cells.Developmental enhancement of adenylate kinase-AMPK metabolic signaling axis supports stem cell cardiac differentiation.Signal transduction by mitochondrial oxidants.Metabolic regulation of redox status in stem cells.The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.Mitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.AMPK at the nexus of energetics and aging.LKB1 preserves genome integrity by stimulating BRCA1 expression.Role of reactive oxygen species in the radiation response of human hematopoietic stem/progenitor cells.Stem cells and the impact of ROS signaling.Liver kinase B1 suppresses lipopolysaccharide-induced nuclear factor κB (NF-κB) activation in macrophages

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Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

http://www.wikidata.org/entity/Q34679984

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

@wuu

name

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@ast

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@en

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@nl

type

label

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@ast

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@en

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@nl

prefLabel

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@ast

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@en

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@nl

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Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.

@en

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Boyi Gan

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Eliot Fletcher-Sananikone

http://www.w3.org/2001/XMLSchema#string

Ergün Sahin

http://www.w3.org/2001/XMLSchema#string

Jian Hu

http://www.w3.org/2001/XMLSchema#string

Li Zhuang

http://www.w3.org/2001/XMLSchema#string

Ronald A Depinho

http://www.w3.org/2001/XMLSchema#string

Shan Jiang

http://www.w3.org/2001/XMLSchema#string

Simona Colla

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Y Alan Wang

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Yingchun Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

Hematopoiesis: an evolving paradigm for stem cell biology

Stem cells and their niches.

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.

LKB1-dependent signaling pathways.

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701-704

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scholarly article

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10.1038/NATURE09595

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7324

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468

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1037784061

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21124456

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3058342

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