Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.
about
Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransductionCadmium-induced ototoxicity in rat cochlear organotypic culturesIntestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4).Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.Review series: The cell biology of hearingAutosomal recessive nonsyndromic deafness genes: a reviewLocalization of inner hair cell mechanotransducer channels using high-speed calcium imaging.Cadherins and mechanotransduction by hair cellsMaking an effort to listen: mechanical amplification in the earGenetics of Nonsyndromic Congenital Hearing LossSensing sound: molecules that orchestrate mechanotransduction by hair cellsMyosins in cell junctionsSensory mechanotransduction at membrane-matrix interfacesStructures of usher syndrome 1 proteins and their complexesThe effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cellsConserved expression of vertebrate microvillar gene homologs in choanocytes of freshwater sponges.Prey capture and phagocytosis in the choanoflagellate Salpingoeca rosettaEvidence for changes in beta- and gamma-actin proportions during inner ear hair cell lifeStructural determinants of cadherin-23 function in hearing and deafnessStructure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily membersStructure of a force-conveying cadherin bond essential for inner-ear mechanotransductionCrystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkersMechanically Activated Ion ChannelsHarmonin (Ush1c) is required in zebrafish Müller glial cells for photoreceptor synaptic development and functionIntegrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death.Hair bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase PTPRQMyosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransductionCyclic nucleotide-gated channel α-3 (CNGA3) interacts with stereocilia tip-link cadherin 23 + exon 68 or alternatively with myosin VIIa, two proteins required for hair cell mechanotransductionCalcium-dependent binding of HCN1 channel protein to hair cell stereociliary tip link protein protocadherin 15 CD3HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domainTMHS is an integral component of the mechanotransduction machinery of cochlear hair cellsParallel evolution of auditory genes for echolocation in bats and toothed whalesAnomalous Brownian motion discloses viscoelasticity in the ear's mechanoelectrical-transduction apparatusHCN channels are not required for mechanotransduction in sensory hair cells of the mouse inner ear.The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammalsIntegration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains.
P2860
Q22337239-3C8900C9-87F4-4220-ABC3-CA44A28574F0Q23913601-FCE11576-9B2C-4E5A-B744-08670D395C46Q24294411-2B442E21-AA14-4848-B96E-786C69D2967DQ24294638-3FC2C69F-DE93-4B75-8C66-CAF97AD24095Q24596426-A34F3C3C-7B98-404E-87F5-DDDB4541AA7CQ24601353-732809F6-D626-4EE4-990A-F958C7DF268AQ24611997-B8636A01-2D9E-4E1A-A9FD-50B522D34EF4Q24647513-C6B4EAE9-1978-4FA4-9DF4-8D57C28048C7Q24649559-A58D8786-904E-4C9D-8FFD-EEF4A8A66A45Q24654219-7778BEEF-7072-4C3B-92D8-627EA29911B2Q26753842-9121DCB0-E6A9-4FBD-A5B1-37FE01571D74Q26866077-5BE4FD9E-D023-4B14-9910-28FFFFBE9EF2Q27004163-E5470F95-DB1E-4977-9062-991FF94B0A36Q27011942-FDD80764-6EF6-4121-88A1-791832B7F54CQ27023615-FE3AD785-E947-4CD1-9200-6A27FBFDD5AAQ27308725-9ADC0522-9EEB-480E-AD16-E72C6DDC2E9DQ27323200-16935FAD-BAA3-4C0C-9348-2F9FE84BF64EQ27335976-D154DA53-0DE0-4614-A813-815D3A188561Q27336425-374AA6AD-3052-4E80-ADAA-868CD9570626Q27660584-304C505D-BCF3-4BBF-B0C4-218992706CEEQ27661886-F6F270B6-EB73-4045-B271-83FBC971C5EFQ27675024-71B3B943-9D6E-4775-994D-6E1648CC5C34Q27676228-8E2ED9DA-B115-4F6C-AB32-8AD227495A23Q28084779-69282496-8CA0-4F5A-8B92-9F54440B2670Q28243260-27B0822F-A3D6-4B61-AC50-EB600C536898Q28485274-31AD5C01-46BB-4361-8496-1309A6F059ACQ28509821-238A68FD-F8E0-486D-9F68-D92FBF06C4EAQ28569812-8AEFF877-D8A3-4995-BCB3-B4B737FBFEFDQ28570825-A8ABCE83-65CB-49FB-987E-49A8EFB2E4A5Q28580932-3D45EC35-EA22-40A0-9E0E-836EE6A62051Q28584355-0754FA8C-DD66-469D-89F1-4B898A787930Q28590789-FCCD1DE7-A048-4625-B0FA-5DEC9948232BQ28593852-6D850EE7-44CC-43DC-B81E-F42533E98191Q28727824-80D2DD59-A41F-4EAF-B737-DFC1A97E591BQ28731745-C714C2E7-A8F3-4A4B-9E95-478DD5ED6F1FQ28749479-2FDA7FBE-6E75-418B-AEB6-C2F4BBE87A64Q28830903-5BB1F0FC-1C28-4C69-80FC-126083AC1310Q30354585-B54FEEBC-1586-40DD-B99E-F48CE5EEF3E4Q30354602-97BD4B15-7E18-46E4-9A7D-D7A26EF8BC0EQ30361176-87B88E65-A5AF-461D-B3A0-0CDE683A07B9
P2860
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@ast
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@en
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@nl
type
label
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@ast
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@en
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@nl
prefLabel
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@ast
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@en
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@nl
P2093
P356
P1433
P1476
Cadherin 23 and protocadherin ...... laments in sensory hair cells.
@en
P2093
Bechara Kachar
Elizabeth M Wilson-Kubalek
Hirofumi Sakaguchi
Joshua Tokita
Piotr Kazmierczak
Ronald A Milligan
Ulrich Müller
P2888
P356
10.1038/NATURE06091
P407
P577
2007-09-01T00:00:00Z
P5875
P6179
1040787924