Endonuclease G: a role for the enzyme in recombination and cellular proliferation
about
Mutagenesis identifies the critical amino acid residues of human endonuclease G involved in catalysis, magnesium coordination, and substrate specificityNo death without life: vital functions of apoptotic effectorsEndonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regionsStructural Insights into Apoptotic DNA Degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegansOxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease GEXOG, a novel paralog of Endonuclease G in higher eukaryotesSelective mitochondrial DNA degradation following double-strand breaksHerpes simplex virus-1 induces expression of a novel MxA isoform that enhances viral replication.Uptake of foreign nucleic acids in kidney tubular epithelial cells deficient in proapoptotic endonucleases.Microarray-based fluorescence assay of endonuclease functionality and inhibition.Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombinationBCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasionApoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repairPathways involved in interleukin-1β-mediated murine cardiomyocyte apoptosis.Non-apoptotic functions of apoptosis-regulatory proteins.Structural variability of the herpes simplex virus 1 genome in vitro and in vivo.The role of DNA exonucleases in protecting genome stability and their impact on ageing.Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy.Replication and recombination of herpes simplex virus DNAKilling of cancer cells through the use of eukaryotic expression vectors harbouring genes encoding nucleases and ribonuclease inhibitor.The Drosophila melanogaster Gene cg4930 Encodes a High Affinity Inhibitor for Endonuclease G.1,4-dihydroxy-2-naphthoic Acid Induces Apoptosis in Human Keratinocyte: Potential Application for Psoriasis Treatment.Cold-inducible RNA-binding protein through TLR4 signaling induces mitochondrial DNA fragmentation and regulates macrophage cell death after trauma.The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death.Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5.Curcumin-enhanced chemosensitivity of FDA-approved platinum (II)-based anti-cancer drugs involves downregulation of nuclear endonuclease G and NF-κB as well as induction of apoptosis and G2/M arrest.
P2860
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P2860
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@ast
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@en
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@nl
type
label
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@ast
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@en
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@nl
prefLabel
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@ast
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@en
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@nl
P2860
P356
P1476
Endonuclease G: a role for the enzyme in recombination and cellular proliferation
@en
P2093
I Robert Lehman
Ke-Jung Huang
P2860
P304
P356
10.1073/PNAS.0603445103
P407
P50
P577
2006-06-05T00:00:00Z