Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine.
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Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in miceCalcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraineTreatment of migraine attacks based on the interaction with the trigemino-cerebrovascular systemMigraine in the era of precision medicineThe TRPA1 channel in migraine mechanism and treatmentProinflammatory mediators and migraine pathogenesis: moving towards CGRP as a target for a novel therapeutic classNeurovascular contributions to migraine: Moving beyond vasodilationEndosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteriesCalcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation.Calcitonin gene-related peptide receptor antagonists for the treatment of migraine: a patent review.Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974).Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.Update in new medications for primary care.Possible sites of action of the new calcitonin gene-related peptide receptor antagonists.Eccentric muscle contraction and stretching evoke mechanical hyperalgesia and modulate CGRP and P2X(3) expression in a functionally relevant mannerCombined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?Pathophysiology of autism spectrum disorders: revisiting gastrointestinal involvement and immune imbalanceTherapeutic effects and safety of olcegepant and telcagepant for migraine: A meta-analysis.Possible site of action of CGRP antagonists in migraine.One hundred years of migraine research: major clinical and scientific observations from 1910 to 2010.Diencephalic and brainstem mechanisms in migraine.Analysis of the proteolysis of bioactive peptides using a peptidomics approach.The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.The Dose Proportionality of Telcagepant after Administration of Single Oral and Intravenous Doses in Healthy Adult SubjectsTargeting TRP channels for novel migraine therapeutics.CGRP receptor antagonists: an expanding drug class for acute migraine?Pearls and pitfalls in experimental in vivo models of migraine: dural trigeminovascular nociception.The vascular theory of migraine--a great story wrecked by the facts.Finding new drug targets for the treatment of migraine attacks.Changes in calcitonin gene-related peptide (CGRP) receptor component and nitric oxide receptor (sGC) immunoreactivity in rat trigeminal ganglion following glyceroltrinitrate pretreatment.Neurologic bases for comorbidity of balance disorders, anxiety disorders and migraine: neurotherapeutic implicationsA randomized, double-blind, placebo-controlled study of breath powered nasal delivery of sumatriptan powder (AVP-825) in the treatment of acute migraine (The TARGET Study).Intraganglionic signaling as a novel nasal-meningeal pathway for TRPA1-dependent trigeminovascular activation by inhaled environmental irritants.Calcitonin gene-related peptide (CGRP): a new target for migraineDevelopment of anti-migraine therapeutics using the capsaicin-induced dermal blood flow model.Effect of CGRP and sumatriptan on the BOLD response in visual cortex.Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level.Isolation of Potent CGRP Neutralizing Antibodies Using Four Simple Assays.Emerging peripheral receptor targets for deep-tissue craniofacial pain therapies.Calcitonin gene-related peptide antagonism for acute treatment of migraine: a meta-analysis.
P2860
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P2860
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Randomized controlled trial of ...... n acute treatment of migraine.
@ast
Randomized controlled trial of ...... n acute treatment of migraine.
@en
Randomized controlled trial of ...... n acute treatment of migraine.
@nl
type
label
Randomized controlled trial of ...... n acute treatment of migraine.
@ast
Randomized controlled trial of ...... n acute treatment of migraine.
@en
Randomized controlled trial of ...... n acute treatment of migraine.
@nl
prefLabel
Randomized controlled trial of ...... n acute treatment of migraine.
@ast
Randomized controlled trial of ...... n acute treatment of migraine.
@en
Randomized controlled trial of ...... n acute treatment of migraine.
@nl
P2093
P1433
P1476
Randomized controlled trial of ...... n acute treatment of migraine.
@en
P2093
A M Rapoport
L K Mannix
MK-0974 Protocol 004 study group
P304
P356
10.1212/01.WNL.0000286940.29755.61
P407
P577
2007-10-03T00:00:00Z