eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model.
about
Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunctionEmerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and DiseaseUBA1: At the Crossroads of Ubiquitin Homeostasis and NeurodegenerationRetrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and diseaseCorticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 FunctionEvidence for an early innate immune response in the motor cortex of ALS.Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortexVisualization of Sensory Neurons and Their Projections in an Upper Motor Neuron Reporter Line.Comprehensive Corticospinal Labeling with mu-crystallin Transgene Reveals Axon Regeneration after Spinal Cord Trauma in ngr1-/- Mice.Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanismsHealthy and diseased corticospinal motor neurons are selectively transduced upon direct AAV2-2 injection into the motor cortex.Marked changes in dendritic structure and spine density precede significant neuronal death in vulnerable cortical pyramidal neuron populations in the SOD1(G93A) mouse model of amyotrophic lateral sclerosisCross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology.Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.Moving forward in clinical trials for ALS: motor neurons lead the way please.Complementary feature selection from alternative splicing events and gene expression for phenotype prediction.Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALSTreatment of amyotrophic lateral sclerosis: lessons learned from many failures.Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model.Incorporating upper motor neuron health in ALS drug discovery.THEME 9IN VIVOEXPERIMENTAL MODELSTHEME 10IN VIVOEXPERIMENTAL MODELS
P2860
Q26741828-22EEDDCF-0964-4F96-AA9E-2579A5E57D75Q26769059-D86076E1-1347-44A9-8EB4-F62531F32218Q26782551-E0C916F7-F72F-4540-978E-4A7FACCCFB76Q26823894-5D288372-1C41-4814-85F8-71E57B00B721Q27302932-961CC913-73C0-4392-B8CE-F4D96D0B29B1Q33837511-8625E506-061F-4D1F-B31B-C078E76507BBQ34983540-4D67FFAE-C868-42CC-ACA7-173021B498E4Q35723883-84606C53-D6C7-40C7-9529-65AC760A9424Q36290079-B590EDD9-2CC1-4F98-946E-F2B3FDFDDED3Q36608848-EEAEEBC4-1ACA-4D69-AB6E-EC245BA5BAC6Q36649800-34A75AD5-5908-4B77-A2DF-38078788C9C9Q37150806-BEEAE25F-5E6C-44C5-8B6B-91683827E524Q37337195-1D4BD0E4-B98B-4EB1-96CB-60F247815CB3Q37534101-47F444AA-F98D-43F8-A730-A5F686ADD620Q38156505-3D6D1243-A72F-4C2A-93BE-527C433D3B8EQ39429465-ECFDD20C-4D9E-4937-9282-31D27578AFEDQ41924656-D797CE03-738E-4EF6-BF4C-A48AD0B93FADQ42109528-D8C609EA-A57B-4F51-B008-67C21448AD97Q47118168-5BB8FAF5-4F88-46F8-A221-92C875C4A859Q50055247-B7A1B36D-BB67-4F77-8075-E2E8C177104BQ58270197-5FF08C3C-8BA5-4CFA-8B6C-185DEA4E5E51Q58273185-90646D65-F3FE-4DA8-B8B6-A03E99890ADC
P2860
eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@ast
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@en
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@nl
type
label
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@ast
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@en
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@nl
prefLabel
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@ast
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@en
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@nl
P2093
P2860
P1476
eGFP expression under UCHL1 pr ...... neurons in an ALS mouse model.
@en
P2093
Ana Milosevic
Baris Genç
C J Heckman
Gordon M G Shepherd
Javier H Jara
Katharina A Quinlan
Marina V Yasvoina
P Hande Özdinler
Patrick L Sheets
P2860
P304
P356
10.1523/JNEUROSCI.2787-12.2013
P407
P577
2013-05-01T00:00:00Z