Close sequence comparisons are sufficient to identify human cis-regulatory elements.
about
Asymmetrical distribution of non-conserved regulatory sequences at PHOX2B is reflected at the ENCODE loci and illuminates a possible genome-wide trendAn alignment-free method to find and visualise rearrangements between pairs of DNA sequencesGenomic views of distant-acting enhancersActivation of Src and transformation by an RPTPĪ± splice mutant found in human tumoursUltraconserved cDNA segments in the human transcriptome exhibit resistance to folding and implicate function in translation and alternative splicingUltraconservation identifies a small subset of extremely constrained developmental enhancersA single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye colorThe landscape of histone modifications across 1% of the human genome in five human cell linesVISTA Enhancer Browser--a database of tissue-specific human enhancersShort sequence motifs, overrepresented in mammalian conserved non-coding sequencesA mammalian conserved element derived from SINE displays enhancer properties recapitulating Satb2 expression in early-born callosal projection neuronsChIP-seq accurately predicts tissue-specific activity of enhancersChIP-Seq identification of weakly conserved heart enhancersRestless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalonCan a few non-coding mutations make a human brain?Noncoding origins of anthropoid traits and a new null model of transposon functionalizationThe opossum genome: insights and opportunities from an alternative mammalBioinformatics for personal genome interpretationThousands of human mobile element fragments undergo strong purifying selection near developmental genesIn vivo enhancer analysis of human conserved non-coding sequencesMultiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis.Vertebrate conserved non coding DNA regions have a high persistence length and a short persistence time.Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes.Adaptive evolution of conserved noncoding elements in mammals.Sequences conserved by selection across mouse and human malaria speciesTFCONES: a database of vertebrate transcription factor-encoding genes and their associated conserved noncoding elementsPrediction of tissue-specific cis-regulatory modules using Bayesian networks and regression treesA meta-analysis of microarray gene expression in mouse stem cells: redefining stemness.An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10.Identifying regulatory elements in eukaryotic genomes.Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergenceIdentifying cis-regulatory sequences by word profile similarityAlgorithms for locating extremely conserved elements in multiple sequence alignments.Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancersDifferential Gene Expression in the Human Brain Is Associated with Conserved, but Not Accelerated, Noncoding Sequences.A functional screen for regulatory elements that improve retroviral vector gene expressionConservation of human microsatellites across 450 million years of evolution.A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus.Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse.Human variation in short regions predisposed to deep evolutionary conservation.
P2860
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P2860
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
description
2006 nĆ® lÅ«n-bĆ»n
@nan
2006 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
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@hyw
2006 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¶Õ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2006幓ć®č«ę
@ja
2006幓č«ę
@yue
2006幓č«ę
@zh-hant
2006幓č«ę
@zh-hk
2006幓č«ę
@zh-mo
2006幓č«ę
@zh-tw
2006幓č®ŗę
@wuu
name
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@ast
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@en
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@nl
type
label
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@ast
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@en
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@nl
prefLabel
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@ast
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@en
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@nl
P2093
P2860
P356
P1433
P1476
Close sequence comparisons are sufficient to identify human cis-regulatory elements.
@en
P2093
Francis Poulin
Len A Pennacchio
Malak Shoukry
Olivier Couronne
Shyam Prabhakar
Veena Afzal
P2860
P304
P356
10.1101/GR.4717506
P577
2006-06-12T00:00:00Z