Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice.
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Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicityImmune tolerance induction to factor IX through B cell gene transfer: TLR9 signaling delineates between tolerogenic and immunogenic B cells.Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy.Gene therapy for haemophilia: prospects and challenges to prevent or reverse inhibitor formation.Transient depletion of B cells in young mice results in activation of regulatory T cells that inhibit development of autoimmune disease in adultsCytokine-conditioned dendritic cells induce humoral tolerance to protein therapy in mice.Exposure to factor VIII protein in the presence of phosphatidylserine induces hypo-responsiveness toward factor VIII challenge in hemophilia A mice.Anti-CD20 as the B-Cell Targeting Agent in a Combined Therapy to Modulate Anti-Factor VIII Immune Responses in Hemophilia a Inhibitor MiceMechanisms of Regulatory B cell Function in Autoimmune and Inflammatory Diseases beyond IL-10.Immune tolerance induction in haemophilia: evidence and the way forward.Progress toward inducing immunologic tolerance to factor VIII.Strategies for reducing inhibitor formation in severe haemophilia.Mechanisms by Which B Cells and Regulatory T Cells Influence Development of Murine Organ-Specific Autoimmune DiseasesFactor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti-factor VIII antibodies in hemophilia A mice.Marginal zone B cells are critical to factor VIII inhibitor formation in mice with hemophilia A.Advances in Overcoming Immune Responses following Hemophilia Gene Therapy.Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated.Successful immune tolerance induction by FVIII in hemophilia A patients with inhibitor may occur without deletion of FVIII-specific T cells.Immunoprotective effect of von Willebrand factor towards therapeutic factor VIII in experimental haemophilia A.Models for assessing immunogenicity and efficacy of new therapeutics for the treatment of haemophilia.Marginal immunogenicity of factor VIII.Combination therapy for inhibitor reversal in haemophilia A using monoclonal anti-CD20 and rapamycin.Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells
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P2860
Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice.
description
2010 nî lūn-bûn
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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@ast
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@en
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@nl
type
label
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@ast
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@en
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@nl
prefLabel
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@ast
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@en
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@nl
P2093
P2860
P921
P1433
P1476
Effect of B-cell depletion usi ...... an FVIII in hemophilia A mice.
@en
P2093
Ai-Hong Zhang
David W Scott
Jonathan Skupsky
P2860
P304
P356
10.1182/BLOOD-2010-06-293324
P407
P577
2010-12-15T00:00:00Z