Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.
about
Phyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis GiganteaUnique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalisThe insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channelsA distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1aPain genesAlternative splicing in the voltage-gated sodium channel DmNav regulates activation, inactivation, and persistent current.Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels.Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin.Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures.Spider-venom peptides as bioinsecticidesPyrethroids differentially alter voltage-gated sodium channels from the honeybee central olfactory neurons.Analysis of the action of lidocaine on insect sodium channels.Molecular determinants on the insect sodium channel for the specific action of type II pyrethroid insecticides.A negative charge in transmembrane segment 1 of domain II of the cockroach sodium channel is critical for channel gating and action of pyrethroid insecticidesIdentification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides.Molecular and functional characterization of voltage-gated sodium channel variants from Drosophila melanogasterMolecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb.A voltage-gated calcium-selective channel encoded by a sodium channel-like geneRNA editing generates tissue-specific sodium channels with distinct gating properties.Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel.Substitutions in the domain III voltage-sensing module enhance the sensitivity of an insect sodium channel to a scorpion beta-toxinRegulation of membrane excitability: a convergence on voltage-gated sodium conductance.An important role of a pyrethroid-sensing residue F1519 in the action of the N-alkylamide insecticide BTG 502 on the cockroach sodium channel.Molecular characterization and functional expression of the DSC1 channel.De novo assembly of a transcriptome for Calanus finmarchicus (Crustacea, Copepoda)--the dominant zooplankter of the North Atlantic OceanA mutation in the intracellular loop III/IV of mosquito sodium channel synergizes the effect of mutations in helix IIS6 on pyrethroid resistance.Batrachotoxin, pyrethroids, and BTG 502 share overlapping binding sites on insect sodium channels.Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A.Rbfox proteins regulate alternative splicing of neuronal sodium channel SCN8AMolecular biology of insect sodium channels and pyrethroid resistance.Multiple sodium channel variants in the mosquito Culex quinquefasciatus.Three mutations identified in the voltage-sensitive sodium channel alpha-subunit gene of permethrin-resistant human head lice reduce the permethrin sensitivity of house fly Vssc1 sodium channels expressed in Xenopus oocytes.Insight into the Mode of Action of Haedoxan A from Phryma leptostachya.Insect sodium channels and insecticide resistance.A novel Na+ channel splice form contributes to the regulation of an androgen-dependent social signalDiversity and frequency of kdr mutations within Anopheles sinensis populations from Guangxi, ChinaUse of non-mammalian alternative models for neurotoxicological studyMolecular characterization and alternative splicing of a sodium channel and DSC1 ortholog genes in Liposcelis bostrychophila Badonnel (Psocoptera: Liposcelididae).Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides
P2860
Q21129291-E8A3753D-7201-4776-8DF5-05104B223127Q24598512-310298FA-7151-4684-91C8-865473F930C8Q27676741-56C41E4D-4328-49DE-810F-9735F79B9A76Q27684660-D11FB849-6319-4596-999C-E25263E63D7EQ28473018-E579F00B-D975-4113-84B3-7F924A507480Q30379170-6D10BE3C-F404-4B10-B9BA-5DB7D586E59BQ33553331-D5E9A2D2-3212-49E5-AD94-11653C36B453Q33796526-849DCA23-9CE9-4871-9930-BCC92949B5EAQ33936573-663A286C-3459-4A03-8A61-1D7E83E3E4AFQ34152362-D92BDDA2-37C8-40B6-8492-3C0D71AFB26CQ34319661-54E91FED-3FC2-44E7-8B68-330416EEBD94Q34497462-57C44BFC-3766-4E82-B07C-9D0A9A2AEC2EQ34498381-341E73BE-5A0B-4EBB-8011-E8D51932C156Q34639874-50A1D052-43AE-4448-898E-5A306A2E2938Q34640710-74BF350E-4CCF-465D-80E8-D40219F091DFQ34667208-AAD840DF-2E2C-4D21-9BBF-4962EB35D25BQ34667346-84EBBD98-F3F9-4FE3-990F-D2277764A9D3Q34669988-57ADE2F9-7C86-45A9-BFF9-6AD33CC4DB6DQ34731442-86C53FF3-77D8-4A1C-95AE-60084A713797Q34731490-05304B88-37DD-4511-A174-31595B686D03Q34787096-34E2BB42-CBB8-4F8F-B278-AE754F1388CBQ34963077-F8FBA30B-3DC6-42F4-97A9-65D3D5F6C8D0Q35024719-AA32C075-8B48-40D4-B567-F04FDDAD5B11Q35056655-CF85C84C-16AD-4B93-B191-55B7D5F2B255Q35057907-4B9BAE81-5729-438F-97D7-B89C8B2AD8CEQ35106142-44B23CC1-5EE9-4B1E-8E81-90701F78ECEFQ35156399-17A2C18F-8AEC-4C76-BAC3-34BD7A27005DQ35188075-16BDE165-4AE9-4C87-9C1A-4D32D049DEBAQ35752646-73BA1887-629F-419C-AFAD-C41998B771AFQ35754047-FC9ACF46-3F3E-4092-81D2-2D29604F29DDQ35795273-D120C44B-2827-41AC-88F3-4E286A29B614Q36382300-D55F5436-4521-495A-B7E0-D4E1EF5E1FFCQ36580002-8814FDEB-1F93-4CCB-9686-619C70C39E7BQ36638349-784212EF-9DD6-46BC-AFCE-5A42CBFBD620Q36700565-6FA40595-C71A-49CD-A40D-35529FAEBD40Q37042444-4D05160F-3499-4211-B1E4-13FDDF4FE140Q37178307-E861E63C-6BCA-456C-955F-70814CB95F9EQ37185724-BE1461CB-CFE2-4BC9-9F2B-1C9EBAC91EAFQ37249266-C540AE32-23B9-45B8-8016-1E289BBFBD28Q37359094-7DF19C00-CF07-4EE4-B63B-2B03E864B12E
P2860
Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Alternative splicing of an ins ...... ally distinct sodium channels.
@ast
Alternative splicing of an ins ...... ally distinct sodium channels.
@en
Alternative splicing of an ins ...... ally distinct sodium channels.
@nl
type
label
Alternative splicing of an ins ...... ally distinct sodium channels.
@ast
Alternative splicing of an ins ...... ally distinct sodium channels.
@en
Alternative splicing of an ins ...... ally distinct sodium channels.
@nl
prefLabel
Alternative splicing of an ins ...... ally distinct sodium channels.
@ast
Alternative splicing of an ins ...... ally distinct sodium channels.
@en
Alternative splicing of an ins ...... ally distinct sodium channels.
@nl
P2093
P2860
P1476
Alternative splicing of an ins ...... ally distinct sodium channels.
@en
P2093
Alan L Goldin
Jianguo Tan
Yoshiko Nomura
P2860
P304
P407
P577
2002-07-01T00:00:00Z