Regulation of substrate utilization by the mitochondrial pyruvate carrier - Wikidata - awgldk - TriplyDB

Regulation of substrate utilization by the mitochondrial pyruvate carrier

Regulation of substrate utilization by the mitochondrial pyruvate carrier

http://www.wikidata.org/entity/Q34710980

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Fundamentals of cancer metabolism Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics A roadmap for interpreting (13)C metabolite labeling patterns from cells Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes.Metabolic rewiring in melanoma Mitochondrial pyruvate transport: a historical perspective and future research directions Metabolic pathways promoting cancer cell survival and growth CRY2 and FBXL3 Cooperatively Degrade c-MYC.Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier.Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.Identification and Verification of Potential Therapeutic Target Genes in Berberine-Treated Zucker Diabetic Fatty Rats through Bioinformatics Analysis MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer Cancer's Fuel Choice: New Flavors for a Picky Eater Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment.Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer.Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas.Mitochondria as biosynthetic factories for cancer proliferation.Chicken or the egg: Warburg effect and mitochondrial dysfunction.The TZD insulin sensitizer clue provides a new route into diabetes drug discovery.Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.A plant/fungal-type phosphoenolpyruvate carboxykinase located in the parasite mitochondrion ensures glucose-independent survival of Toxoplasma gondii.Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells.Pyruvate and Metabolic Flexibility: Illuminating a Path Toward Selective Cancer Therapies Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling.Mitochondrial pyruvate carrier function and cancer metabolism.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Traditional and novel tools to probe the mitochondrial metabolism in health and disease.Functional Properties of the Mitochondrial Carrier System.Mitochondrial Bioenergetics and Dysfunction in Failing Heart.Metabolic remodeling: a pyruvate transport affair.An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion.Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP.Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death.Neurons eat glutamate to stay alive.MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer.

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P2860

Regulation of substrate utilization by the mitochondrial pyruvate carrier

http://www.wikidata.org/entity/Q34710980

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2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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name

Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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type

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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prefLabel

Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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J.MOLCEL.2014.09.024

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Regulation of substrate utilization by the mitochondrial pyruvate carrier

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Ajit S Divakaruni

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Christian M Metallo

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Nathaniel M Vacanti

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Robert R Henry

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Seth J Parker

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Theodore P Ciaraldi

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P2860

Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

Brain fuel metabolism, aging, and Alzheimer's disease

Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions

Targeting mitochondrial oxidative metabolism as an approach to treat heart failure

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.

Identification and functional expression of the mitochondrial pyruvate carrier.

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

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Courtney R Green

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