The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step
about
HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake.Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections.Activation of rho GTPases by cytotoxic necrotizing factor 1 induces macropinocytosis and scavenging activity in epithelial cellsClathrin-dependent entry of a gingipain adhesin peptide and Porphyromonas gingivalis into host cellsIntracellular trafficking of AIP56, an NF-κB-cleaving toxin from Photobacterium damselae subsp. piscicidaReovirus cell entry requires functional microtubules.Cytotoxic necrotizing factor type 1 delivered by outer membrane vesicles of uropathogenic Escherichia coli attenuates polymorphonuclear leukocyte antimicrobial activity and chemotaxis.Caveolae/raft-dependent endocytosis.Targeting of host-cell ubiquitin and ubiquitin-like pathways by bacterial factors.Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2Two domains of cytotoxic necrotizing factor type 1 bind the cellular receptor, laminin receptor precursor protein.Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranesRho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology.The Rho-activating CNF1 toxin from pathogenic E. coli: a risk factor for human cancer development?Mechanisms of microbial traversal of the blood-brain barrier.What a difference a Dalton makes: bacterial virulence factors modulate eukaryotic host cell signaling systems via deamidationThe cytotoxic necrotizing factor of Yersinia pseudotuberculosis (CNFY) enhances inflammation and Yop delivery during infection by activation of Rho GTPases.Multifaceted interactions of bacterial toxins with the gastrointestinal mucosa.Cytotoxic Necrotizing Factors (CNFs)-A Growing Toxin Family.Escherichia coli cytotoxic necrotizing factor 1 (CNF1): toxin biology, in vivo applications and therapeutic potential.The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators.The E. coli CNF1 as a pioneering therapy for the central nervous system diseases.Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin.Enhancement of mitochondrial ATP production by the Escherichia coli cytotoxic necrotizing factor 1.Localization of functional domains of the mitogenic toxin of Pasteurella multocida.Escherichia coli producing CNF1 toxin hijacks Tollip to trigger Rac1-dependent cell invasion.Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: potential cytotoxicity for intestinal epithelial cells.Cytotoxic necrotizing factor 1 of Escherichia coli stimulates Rho/Rho-kinase-dependent myosin light-chain phosphorylation without inactivating myosin light-chain phosphatase in endothelial cells.Cleavage of Escherichia coli cytotoxic necrotizing factor 1 is required for full biologic activity.The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol.Determinants of pH-dependent modulation of translocation in dermonecrotic G-protein-deamidating toxins.Change in substrate specificity of cytotoxic necrotizing factor unmasks proteasome-independent down-regulation of constitutively active RhoA.Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum.Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity.67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells.Intracellular trafficking of Pseudomonas ExoS, a type III cytotoxin.Expression of cnf1 by Escherichia coli J96 involves a large upstream DNA region including the hlyCABD operon, and is regulated by the RfaH protein.Bacterial Toxins and Targeted Brain Therapy: New Insights from Cytotoxic Necrotizing Factor 1 (CNF1).
P2860
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P2860
The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
The p21 Rho-activating toxin c ...... nt membrane translocation step
@ast
The p21 Rho-activating toxin c ...... nt membrane translocation step
@en
The p21 Rho-activating toxin c ...... nt membrane translocation step
@nl
type
label
The p21 Rho-activating toxin c ...... nt membrane translocation step
@ast
The p21 Rho-activating toxin c ...... nt membrane translocation step
@en
The p21 Rho-activating toxin c ...... nt membrane translocation step
@nl
prefLabel
The p21 Rho-activating toxin c ...... nt membrane translocation step
@ast
The p21 Rho-activating toxin c ...... nt membrane translocation step
@en
The p21 Rho-activating toxin c ...... nt membrane translocation step
@nl
P2093
P2860
P356
P1476
The p21 Rho-activating toxin c ...... nt membrane translocation step
@en
P2093
P2860
P304
P356
10.1091/MBC.11.5.1775
P577
2000-05-01T00:00:00Z