The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin. - Wikidata - awgldk - TriplyDB

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

http://www.wikidata.org/entity/Q34718745

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Mitochondrial fatty acid oxidation in obesity Sirtuin 1 and sirtuin 3: physiological modulators of metabolism The role of the p53 tumor suppressor in metabolism and diabetes Ghrelin.The cellular and molecular bases of leptin and ghrelin resistance in obesity.Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice.Neonatal events, such as androgenization and postnatal overfeeding, modify the response to ghrelin.Ghrelin modulates the fMRI BOLD response of homeostatic and hedonic brain centers regulating energy balance in the rat.Therapeutic Potential of Targeting the Ghrelin Pathway.Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis.Upregulation and nuclear translocation of testicular ghrelin protects differentiating spermatogonia from ionizing radiation injury.Hypothalamic KLF4 mediates leptin's effects on food intake via AgRP Minireview: Central Sirt1 regulates energy balance via the melanocortin system and alternate pathways.The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats.Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin.Heterozygous deficiency of endoglin decreases insulin and hepatic triglyceride levels during high fat diet Female Nur77-deficient mice show increased susceptibility to diet-induced obesity.The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation.Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity.Daytime sleepiness in obesity: mechanisms beyond obstructive sleep apnea--a review.Systemic regulation of mammalian ageing and longevity by brain sirtuins.A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53.Mice lacking δ-opioid receptors resist the development of diet-induced obesity Sirtuin biology and relevance to diabetes treatment.Cellular signal mechanisms of reward-related plasticity in the hippocampus.Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin.A low-salt diet increases the expression of renal sirtuin 1 through activation of the ghrelin receptor in rats.Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor.Calorie restriction and sirtuins revisited Structure and physiological actions of ghrelin Nutrient Sensing Systems in Fish: Impact on Food Intake Regulation and Energy Homeostasis.Is p53 Involved in Tissue-Specific Insulin Resistance Formation?SIRT1 and other sirtuins in metabolism.Hypothalamic control of lipid metabolism: focus on leptin, ghrelin and melanocortins.Lysine acetylation in obesity, diabetes and metabolic disease.Recent Insights into the Role of Hypothalamic AMPK Signaling Cascade upon Metabolic Control.SIRT1 in neurodevelopment and brain senescence.AMPK: regulating energy balance at the cellular and whole body levels.

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P2860

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

http://www.wikidata.org/entity/Q34718745

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

@wuu

name

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@ast

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@en

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

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type

label

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@ast

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@en

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@nl

prefLabel

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@ast

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@en

The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@nl

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The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin.

@en

P2093

Amparo Romero

http://www.w3.org/2001/XMLSchema#string

Carlos Diéguez

http://www.w3.org/2001/XMLSchema#string

Douglas A Velásquez

http://www.w3.org/2001/XMLSchema#string

Gloria Martínez

http://www.w3.org/2001/XMLSchema#string

Iria G Dopeso-Reyes

http://www.w3.org/2001/XMLSchema#string

Katia D Boit

http://www.w3.org/2001/XMLSchema#string

María J Vázquez

http://www.w3.org/2001/XMLSchema#string

P2860

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Ghrelin increases intake of rewarding food in rodents

SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

AMP-activated protein kinase plays a role in the control of food intake

SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

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1177-1185

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scholarly article

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10.2337/DB10-0802

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4

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60

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Ruben Nogueiras

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2011-03-08T00:00:00Z

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50348220

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21386086

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3064091

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