Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.
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Targets for Ibrutinib Beyond B Cell MalignanciesIbrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets.Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.Targeting Bruton's tyrosine kinase signaling as an emerging therapeutic agent of B-cell malignanciesBreaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia.Inducible tyrosine kinase inhibitors: a review of the patent literature (2010 - 2013).Quantitative structure-activity relationship study on BTK inhibitors by modified multivariate adaptive regression spline and CoMSIA methods.Ibrutinib-A double-edge sword in cancer and autoimmune disorders.A three-signal model of T-cell lymphoma pathogenesisThe role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling.A general approach for the development of fluorogenic probes suitable for no-wash imaging of kinases in live cells.ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation.Nonreceptor tyrosine kinases ITK and BTK negatively regulate mast cell proinflammatory responses to lipopolysaccharide.Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.Interleukin-2-inducible T-cell kinase (ITK) targeting by BMS-509744 does not affect cell viability in T-cell prolymphocytic leukemia (T-PLL).Bruton Tyrosine Kinase Inhibition Attenuates Liver Damage in a Mouse Warm Ischemia and Reperfusion Model.Bruton's tyrosine kinase (Btk) is a useful marker for Hodgkin and B cell non-Hodgkin lymphoma.Membrane translocation of Bruton kinase in multiple myeloma cells is associated with osteoclastogenic phenotype in bone metastatic lesions.Use of Laplacian Heat Diffusion Algorithm to Infer Novel Genes With Functions Related to Uveitis
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P2860
Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@ast
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@en
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@nl
type
label
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@ast
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@en
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@nl
prefLabel
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@ast
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@en
Inhibitors of BTK and ITK: sta ...... ity and inflammatory diseases.
@nl
P2860
P356
P1476
Inhibitors of BTK and ITK: sta ...... nity and inflammatory diseases
@en
P2093
P2860
P304
P356
10.1111/SJI.12069
P577
2013-08-01T00:00:00Z