Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses.

Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses.

Item
http://www.wikidata.org/entity/Q34722352
Synthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15Endoplasmic Reticulum Stress and Homeostasis in Reproductive Physiology and Pathology.Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cellsThe proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cellsUSP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment.The isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells.Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy.Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases.Method for measuring the activity of deubiquitinating enzymes in cell lines and tissue samples.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents.Targeting Deubiquitinating Enzymes and Autophagy in Cancer.The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold.Molecular Targets of Active Anticancer Compounds Derived from Marine Sources.Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian CancerDiscovering proteasomal deubiquitinating enzyme inhibitors for cancer therapy: lessons from rational design, nature and old drug reposition
P2860

Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses.

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http://www.wikidata.org/entity/Q34722352
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2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@ast
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@en
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
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type
label
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@ast
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@en
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@nl
prefLabel
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
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Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@en
Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
@nl
P1433
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P2093
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Small-molecule RA-9 inhibits p ...... ng unfolded protein responses.
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P2093
P2860
P304
P31
P356
10.1158/1078-0432.CCR-13-2658
P407
P433
P478
P50
P577
P698
P921
P932