Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. - Wikidata - awgldk - TriplyDB

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

http://www.wikidata.org/entity/Q34724924

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Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A Comparative Analysis Human telomerase contains evolutionarily conserved catalytic and structural subunits A natural product telomerase activator as part of a health maintenance program The telomere syndromes Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones Strict control of telomerase activation using Cre-mediated inversion.Changes in Regenerative Capacity through Lifespan Muscle wasting in myotonic dystrophies: a model of premature aging The short and long telomere syndromes: paired paradigms for molecular medicine Changes in primary lymphoid organs with aging Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy Human adult stem cells from diverse origins: an overview from multiparametric immunophenotyping to clinical applications Rheumatoid arthritis: a role for immunosenescence?The germline/soma dichotomy: implications for aging and degenerative disease Telomerase Activation in Hematological Malignancies Position statement on human aging InTERTesting association between telomerase, mTOR and phytochemicals Variation at the TERT locus and predisposition for cancer Impact of genomic damage and ageing on stem cell function Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer The power of exercise: buffering the effect of chronic stress on telomere length WRN loss induces switching of telomerase-independent mechanisms of telomere elongation Accumulation of DNA damage in the aged hematopoietic stem cell compartment Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells.Telomere shortening is an in vivo marker of myocyte replication and aging.Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization.Longitudinal data on telomere length in leukocytes from newborn baboons support a marked drop in stem cell turnover around 1 year of age.Compartmental architecture and dynamics of hematopoiesis.Aging and replicative senescence have related effects on human stem and progenitor cells.Telomere biology in healthy aging and disease.The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa.RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cells Syndromes of telomere shortening Role of telomerase in cellular proliferation and cancer.Commitment and differentiation of lung cell lineages.Telomerase deficiency does not alter bleomycin-induced fibrosis in mice In vivo telomere dynamics of human hematopoietic stem cells.Shorter Remission Telomere Length Predicts Delayed Neutrophil Recovery After Acute Myeloid Leukemia Therapy: A Report From the Children's Oncology Group.Human naive and memory T lymphocytes differ in telomeric length and replicative potential.

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P2860

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

http://www.wikidata.org/entity/Q34724924

description

1994 nî lūn-bûn

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1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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1994 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1994年の論文

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1994年学术文章

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1994年学术文章

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1994年学术文章

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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Proceedings of the National Academy of Sciences of the United States of America

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Evidence for a mitotic clock i ...... oss of telomeric DNA with age.

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C B Harley

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P2860

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

Expression of Thy-1 on human hematopoietic progenitor cells

A mutant with a defect in telomere elongation leads to senescence in yeast.

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

Telomeres shorten during ageing of human fibroblasts

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

Telomere length predicts replicative capacity of human fibroblasts

Structure and function of telomeres

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

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