IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma. - Wikidata - awgldk - TriplyDB

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

http://www.wikidata.org/entity/Q34728942

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Present Advances and Future Perspectives of Molecular Targeted Therapy for Osteosarcoma Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers Sustained proliferation in cancer: Mechanisms and novel therapeutic targets Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential Meta-analysis of differentially expressed genes in osteosarcoma based on gene expression data.Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.PTEN deficiency mediates a reciprocal response to IGFI and mTOR inhibition.Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy.The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone CORR Insights(®): Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma.Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-b as Involved in the Pathogenesis of Osteosarcoma FOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression.Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model.Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology.Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.Targeting IGF1R pathway in cancer with microRNAs: How close are we ?Preclinical Effectiveness of Selective Inhibitor of IRS-1/2 NT157 in Osteosarcoma Cell Lines.Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients.Expression of IGFBP6, IGFBP7, NOV, CYR61, WISP1 and WISP2 genes in U87 glioma cells in glutamine deprivation condition.Transcripts Encoding the Androgen Receptor and IGF-Related Molecules Are Differently Expressed in Human Granulosa Cells From Primordial and Primary Follicles

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

http://www.wikidata.org/entity/Q34728942

description

2013 nî lūn-bûn

@nan

2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013 թվականի մայիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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type

label

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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prefLabel

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

@ast

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.

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A Bassim Hassan

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Anne-Marie Cleton-Jansen

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Brendy E W M van den Akker

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Elisabeth F P Peterse

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Inge H Briaire-de Bruijn

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Leonardo A Meza-Zepeda

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Marieke L Kuijjer

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Massimo Serra

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Pancras C W Hogendoorn

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P2860

Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances

Bioconductor: open software development for computational biology and bioinformatics

KEGG: kyoto encyclopedia of genes and genomes

A single IGF1 allele is a major determinant of small size in dogs

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation of human K562 leukemia cells

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer

Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup.

R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study

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