GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine - Wikidata - awgldk - TriplyDB

GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

http://www.wikidata.org/entity/Q34729421

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Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as Therapy Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants Antidepressant actions of ketamine: from molecular mechanisms to clinical practice LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment.Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.Ketamine and phencyclidine: the good, the bad and the unexpected.Neuroplasticity underlying the comorbidity of pain and depression NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism.Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress.Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons Novel Glutamatergic Treatments for Severe Mood Disorders.BDNF - a key transducer of antidepressant effects.Ketamine: NMDA Receptors and Beyond.Gene expression alterations in the medial prefrontal cortex and blood cells in a mouse model of depression during menopause Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model.ON or OFF?: Modulating the N-Methyl-D-Aspartate Receptor in Major Depression.Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine New perspectives on the involvement of mTOR in depression as well as in the action of antidepressant drugs.New Treatment Strategies of Depression: Based on Mechanisms Related to Neuroplasticity.KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.Pushing the threshold: How NMDAR antagonists induce homeostasis through protein synthesis to remedy depression.What is the mechanism of Ketamine's rapid-onset antidepressant effect? A concise overview of the surprisingly large number of possibilities.Neurobiological mechanisms of stress resilience and implications for the aged population.Antidepressant Actions of Ketamine Mediated by the Mechanistic Target of Rapamycin, Nitric Oxide, and Rheb.A GluN2B-Selective NMDAR Antagonist Reverses Synapse Loss and Cognitive Impairment Produced by the HIV-1 Protein Tat.Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects.Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders.EphB2 in the Medial Prefrontal Cortex Regulates Vulnerability to Stress.Bidirectional Homeostatic Regulation of a Depression-Related Brain State by Gamma-Aminobutyric Acidergic Deficits and Ketamine Treatment.P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression.How ketamine helps to overcome depression.N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease.Ketamine inside neurons?Memantine and Ketamine Differentially Alter NMDA Receptor Desensitization.Molecular Mechanism and Clinical Relevance of Ketamine as Rapid-Acting Antidepressant.Antagonism at the NR2B subunit of NMDA receptors induces increased connectivity of the prefrontal and subcortical regions regulating reward behavior.GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.Orphan receptor GPR158 controls stress-induced depression.Mechanisms of ketamine action as an antidepressant.

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GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

http://www.wikidata.org/entity/Q34729421

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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GluN2B-containing NMDA recepto ...... depressant actions of ketamine

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Benjamin J Hall

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Chih-Chieh Wang

http://www.w3.org/2001/XMLSchema#string

Elizabeth A Hargroder

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Eric Delpire

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Lingling Yang

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Yihui Zhang

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P2860

FMR1 protein: conserved RNP family domains and selective RNA binding

rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein

Guidance molecules in synapse formation and plasticity

mTOR signaling in growth control and disease

mTOR signaling: at the crossroads of plasticity, memory and disease

Glutamate as a neurotransmitter in the brain: review of physiology and pathology

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway

Behavioral despair in mice: a primary screening test for antidepressants

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e03581

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scholarly article

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10.7554/ELIFE.03581

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3

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Oliver H Miller

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2014-10-23T00:00:00Z

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267739291

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25340958

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