Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing.
about
Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced ActivityEngineering enhanced protein disaggregases for neurodegenerative diseaseDe novo [PSI +] prion formation involves multiple pathways to form infectious oligomers.Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity.Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo.A mathematical model of the dynamics of prion aggregates with chaperone-mediated fragmentationYeast Short-Lived Actin-Associated Protein Forms a Metastable Prion in Response to Thermal Stress.Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104.Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection.Designer protein disaggregases to counter neurodegenerative disease.The [PSI +] yeast prion does not wildly affect proteome composition whereas selective pressure exerted on [PSI +] cells can promote aneuploidy.A dominant-negative mutant inhibits multiple prion variants through a common mechanism.Pathways of cellular proteostasis in aging and disease.[PIN+]ing down the mechanism of prion appearance.
P2860
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P2860
Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Spatial quality control bypass ...... tasis to promote prion curing.
@ast
Spatial quality control bypass ...... tasis to promote prion curing.
@en
Spatial quality control bypass ...... tasis to promote prion curing.
@nl
type
label
Spatial quality control bypass ...... tasis to promote prion curing.
@ast
Spatial quality control bypass ...... tasis to promote prion curing.
@en
Spatial quality control bypass ...... tasis to promote prion curing.
@nl
prefLabel
Spatial quality control bypass ...... tasis to promote prion curing.
@ast
Spatial quality control bypass ...... tasis to promote prion curing.
@en
Spatial quality control bypass ...... tasis to promote prion curing.
@nl
P2093
P2860
P356
P1433
P1476
Spatial quality control bypass ...... tasis to promote prion curing.
@en
P2093
Christine R Langlois
Courtney L Klaips
Tricia R Serio
P2860
P356
10.7554/ELIFE.04288
P407
P577
2014-12-09T00:00:00Z