Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. - Wikidata - awgldk - TriplyDB

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

http://www.wikidata.org/entity/Q34739990

about

Cell Proliferation in Neuroblastoma Diversity-oriented synthetic strategies applied to cancer chemical biology and drug discovery SwitchFinder - a novel method and query facility for discovering dynamic gene expression patterns.Mutations that disrupt PHOXB interaction with the neuronal calcium sensor HPCAL1 impede cellular differentiation in neuroblastoma.Therapeutic strategies to inhibit MYC Profiling deacetylase activities in cell lysates with peptide arrays and SAMDI mass spectrometry.Computational design of a time-dependent histone deacetylase 2 selective inhibitor.Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.Bromodomain and extraterminal inhibition blocks tumor progression and promotes differentiation in neuroblastoma Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.Targeted approaches to childhood cancer: progress in drug discovery and development.Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model.HDACs and HDAC Inhibitors in Cancer Development and Therapy.The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression.Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles.Incorporating genomic, transcriptomic and clinical data: a prognostic and stem cell-like MYC and PRC imbalance in high-risk neuroblastoma.CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.Isoxazole compound ML327 blocks MYC expression and tumor formation in neuroblastoma.Epigenetic regulation of motivated behaviors by histone deacetylase inhibitors.Epigenetic Combination Therapy for Children With Secondary Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML) and Concurrent Solid Tumor Relapse.Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications.Targeting of epigenetic regulators in neuroblastoma.Combination Effect of Silver Nanoparticles and Histone Deacetylases Inhibitor in Human Alveolar Basal Epithelial Cells

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Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

http://www.wikidata.org/entity/Q34739990

description

2013 nî lūn-bûn

@nan

2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի մայիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@ast

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@en

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@nl

type

label

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@ast

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@en

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@nl

prefLabel

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@ast

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@en

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@nl

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P356

J.CHEMBIOL.2013.03.020

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Chemistry and Biology

P1476

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

@en

P2093

Andrew L Kung

http://www.w3.org/2001/XMLSchema#string

Byung-Chul Suh

http://www.w3.org/2001/XMLSchema#string

Christopher F Bassil

http://www.w3.org/2001/XMLSchema#string

Edward Holson

http://www.w3.org/2001/XMLSchema#string

Florence F Wagner

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Giovanni Roti

http://www.w3.org/2001/XMLSchema#string

James E Bradner

http://www.w3.org/2001/XMLSchema#string

Jeremy R Duvall

http://www.w3.org/2001/XMLSchema#string

Jun Qi

http://www.w3.org/2001/XMLSchema#string

Kenneth N Ross

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P2860

Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

Target-oriented and diversity-oriented organic synthesis in drug discovery

The evolving role of natural products in drug discovery

Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase

Chemical phylogenetics of histone deacetylases.

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.

FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma.

Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma

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713-725

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scholarly article

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10.1016/J.CHEMBIOL.2013.03.020

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5

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20

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Kimberly Stegmaier

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2013-05-01T00:00:00Z

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236937794

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23706636

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3919449

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