Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
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Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor targetDNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinomaMultilevel pharmacokinetics-driven modeling of metabolomics data.S-adenosylmethionine in liver health, injury, and cancer.Downregulation of P-cadherin expression in hepatocellular carcinoma induces tumorigenicity.Expression of MTAP inhibits tumor-related phenotypes in HT1080 cells via a mechanism unrelated to its enzymatic function.Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance.Expression and function of methylthioadenosine phosphorylase in chronic liver disease.Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice.Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell LinesMethylthioadenosine (MTA) Regulates Liver Cells Proteome and Methylproteome: Implications in Liver Biology and DiseaseCharacterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant MelanomaPreventative oral methylthioadenosine is anti-inflammatory and reduces DSS-induced colitis in mice.Characterization and Prognostic Significance of Methylthioadenosine Phosphorylase Deficiency in Nasopharyngeal Carcinoma.Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis.Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma.Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cellsRegulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma.Diagnostic value of DNA alteration: loss of heterozygosity or allelic imbalance-promising for molecular staging of prostate cancers.Involvement of the ubiquitin-proteasome system in the formation of experimental postsurgical peritoneal adhesions.Diagnostic and Prognostic Significance of Methionine Uptake and Methionine Positron Emission Tomography Imaging in Gliomas.
P2860
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P2860
Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@ast
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@en
Down-regulation of methylthioadenosine phosphorylase
@nl
type
label
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@ast
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@en
Down-regulation of methylthioadenosine phosphorylase
@nl
prefLabel
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@ast
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@en
Down-regulation of methylthioadenosine phosphorylase
@nl
P2093
P2860
P1476
Down-regulation of methylthioa ...... -5'-methylthioadenosine (MTA).
@en
P2093
Arndt Hartmann
Axel P Stevens
Barbara Czech
Claus Hellerbrand
Georgi Kirovski
Katja Dettmer
Peter J Oefner
Peter Wild
Thomas S Weiss
P2860
P304
P356
10.1016/J.AJPATH.2010.11.059
P407
P577
2011-01-28T00:00:00Z