Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms.
about
Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet.Human cytomegalovirus resistance to antiviral drugsUpdate on human herpesvirus 6 biology, clinical features, and therapySlipping and sliding: frameshift mutations in herpes simplex virus thymidine kinase and drug-resistanceNew strategies against drug resistance to herpes simplex virusCMV: Prevention, Diagnosis and TherapyRational approaches to improving selectivity in drug designPhosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA PolymeraseHow I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipientsMechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activityAntiviral drug resistance: mechanisms and clinical implicationsNovel agents and strategies to treat herpes simplex virus infections.Agents and strategies in development for improved management of herpes simplex virus infection and disease.Antiviral drug resistance of human cytomegalovirus.Diverse herpes simplex virus type 1 thymidine kinase mutants in individual human neurons and Ganglia.Genotypic characterization of the DNA polymerase and sensitivity to antiviral compounds of foscarnet-resistant herpes simplex virus type 1 (HSV-1) derived from a foscarnet-sensitive HSV-1 strain.Recombinant phenotyping of cytomegalovirus UL97 kinase sequence variants for ganciclovir resistance.An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase geneEmerging drugs for varicella-zoster virus infections.Heterogeneity and evolution of thymidine kinase and DNA polymerase mutants of herpes simplex virus type 1: implications for antiviral therapy.Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and managementNon-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin AGenotypic characterization of UL23 thymidine kinase and UL30 DNA polymerase of clinical isolates of herpes simplex virus: natural polymorphism and mutations associated with resistance to antivirals.Quantification of viral DNA and liver enzymes in plasma improves early diagnosis and management of herpes simplex virus hepatitisIdentification of a varicella-zoster virus replication inhibitor that blocks capsid assembly by interacting with the floor domain of the major capsid protein.Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral ResistanceInhibitors of nucleotidyltransferase superfamily enzymes suppress herpes simplex virus replicationLow-level expression and reversion both contribute to reactivation of herpes simplex virus drug-resistant mutants with mutations on homopolymeric sequences in thymidine kinase.Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies.Cytomegalovirus reactivation in critically ill immunocompetent hosts: a decade of progress and remaining challenges.Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infectionsDoes Cytomegalovirus Develop Resistance following Antiviral Prophylaxis and Treatment in Renal Transplant Patients in Kuwait?In vitro-selected drug-resistant varicella-zoster virus mutants in the thymidine kinase and DNA polymerase genes yield novel phenotype-genotype associations and highlight differences between antiherpesvirus drugs.Identification of ribonucleotide reductase mutation causing temperature-sensitivity of herpes simplex virus isolates from whitlow by deep sequencing.Long-term outcomes in patients undergoing vitrectomy for retinal detachment due to viral retinitisExpression of extremely low levels of thymidine kinase from an acyclovir-resistant herpes simplex virus mutant supports reactivation from latently infected mouse trigeminal gangliaAchievements and challenges in antiviral drug discovery.Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex
P2860
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P2860
Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@ast
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@en
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@nl
type
label
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@ast
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@en
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@nl
prefLabel
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@ast
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@en
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@nl
P2093
P1476
Resistance of herpesviruses to ...... acts and molecular mechanisms.
@en
P2093
Christian Gilbert
Guy Boivin
Julie Bestman-Smith
P304
P356
10.1016/S1368-7646(02)00021-3
P577
2002-04-01T00:00:00Z