A single amino acid substitution in herpes simplex virus type 1 VP16 inhibits binding to the virion host shutoff protein and is incompatible with virus growth.

A single amino acid substitution in herpes simplex virus type 1 VP16 inhibits binding to the virion host shutoff protein and is incompatible with virus growth.

Item
http://www.wikidata.org/entity/Q34758139
Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4HShutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesTegument Assembly and Secondary Envelopment of AlphaherpesvirusesTime-dependent transformation of the herpesvirus tegument.Phosphorylation of the VP16 transcriptional activator protein during herpes simplex virus infection and mutational analysis of putative phosphorylation sites.Analysis of the interaction between the essential herpes simplex virus 1 tegument proteins VP16 and VP1/2.Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNATranslocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene.C-terminal trans-activation sub-region of VP16 is uniquely required for forskolin-induced herpes simplex virus type 1 reactivation from quiescently infected-PC12 cells but not for replication in neuronally differentiated-PC12 cells.Role of the VP16-binding domain of vhs in viral growth, host shutoff activity, and pathogenesis.Herpes Simplex Virus 2 Virion Host Shutoff Endoribonuclease Activity Is Required To Disrupt Stress Granule Formation.The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formationThe herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner.Nuclear localizations of the herpes simplex virus type 1 tegument proteins VP13/14, vhs, and VP16 precede VP22-dependent microtubule reorganization and VP22 nuclear importA bimodal switch in global protein translation coupled to eIF4H relocalisation during advancing cell-cell transmission of herpes simplex virus
P2860

A single amino acid substitution in herpes simplex virus type 1 VP16 inhibits binding to the virion host shutoff protein and is incompatible with virus growth.

Item
http://www.wikidata.org/entity/Q34758139
description
2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A single amino acid substituti ...... ncompatible with virus growth.
@ast
A single amino acid substituti ...... ncompatible with virus growth.
@en
A single amino acid substituti ...... ncompatible with virus growth.
@nl
type
label
A single amino acid substituti ...... ncompatible with virus growth.
@ast
A single amino acid substituti ...... ncompatible with virus growth.
@en
A single amino acid substituti ...... ncompatible with virus growth.
@nl
prefLabel
A single amino acid substituti ...... ncompatible with virus growth.
@ast
A single amino acid substituti ...... ncompatible with virus growth.
@en
A single amino acid substituti ...... ncompatible with virus growth.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
A single amino acid substituti ...... ncompatible with virus growth.
@en
P2093
P2860
P304
P31
P356
10.1128/JVI.77.5.2892-2902.2003
P407
P433
P478
P577
P5875
P698
P932