The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
about
Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health scienceEtiologic field effect: reappraisal of the field effect concept in cancer predisposition and progressionThe MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomideStatistical methods for studying disease subtype heterogeneityThe role of DNA methylation as biomarkers in the clinical management of lung cancer.The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort.GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer.HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer.Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme.Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study.A Meta-Regression Method for Studying Etiological Heterogeneity Across Disease Subtypes Classified by Multiple Biomarkers.Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in LungSex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers.Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in GlioblastomaDetection of premalignant bronchial lesions can be significantly improved by combination of advanced bronchoscopic imaging techniquesGenome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomasInvestigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing.Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico.Influence of promoter/enhancer region haplotypes on MGMT transcriptional regulation: a potential biomarker for human sensitivity to alkylating agents.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.DNA methylation and personalized medicine.The SNP rs6441224 influences transcriptional activity and prognostically relevant hypermethylation of RARRES1 in prostate cancer.SNP rs16906252C>T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer.The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients' survival.The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma.
P2860
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P2860
The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2011 թվականի փետրվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@ast
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@en
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@nl
type
label
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@ast
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@en
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@nl
prefLabel
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@ast
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@en
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@nl
P2093
P2860
P1476
The A/G allele of rs16906252 p ...... s and in lung adenocarcinomas.
@en
P2093
Amanda M Bernauer
Carmen S Tellez
Chibo Hong
Christin M Yingling
Christine A Stidley
Elizabeth A Burki
Frank D Gilliland
Joseph F Costello
Kristina G Flores
P2860
P304
P356
10.1158/1078-0432.CCR-10-3026
P407
P577
2011-02-25T00:00:00Z