Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm.
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesNanodiamonds: The intersection of nanotechnology, drug development, and personalized medicineDiagnosis of prostate cancer via nanotechnological approachStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewDeveloping defined culture systems for human pluripotent stem cellsEfficient discovery of anti-inflammatory small-molecule combinations using evolutionary computingSearch algorithms as a framework for the optimization of drug combinations.Statistical metamodeling for revealing synergistic antimicrobial interactionsPrediction of drug combinations by integrating molecular and pharmacological dataStatistical properties and robustness of biological controller-target networksControl of Kaposi's sarcoma-associated herpesvirus reactivation induced by multiple signalsIdentification of drug combinations containing imatinib for treatment of BCR-ABL+ leukemiasA Network-Based Target Overlap Score for Characterizing Drug Combinations: High Correlation with Cancer Clinical Trial ResultsNetwork-based drug discovery by integrating systems biology and computational technologiesMorphological plasticity of bacteria-Open questions.Intelligent Systems and Technology for Integrative and Predictive Medicine: An ACP Approach.Integrated microfluidic devices for combinatorial cell-based assays.Probing cell migration in confined environments by plasma lithographyLeft-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics.Drug-therapy networks and the prediction of novel drug targets.Optimal drug combinations and minimal hitting sets.A formal model for analyzing drug combination effects and its application in TNF-alpha-induced NFkappaB pathwayLipid modulatory activities of Cichorium glandulosum Boiss et Huet are mediated by multiple components within hepatocytes.Combinatorial therapy discovery using mixed integer linear programming.A systems biology approach to identify effective cocktail drugs.Enhanced stochastic optimization algorithm for finding effective multi-target therapeuticsSystematic quantitative characterization of cellular responses induced by multiple signalsEvolving refractory major depressive disorder diagnostic and treatment paradigms: toward closed-loop therapeutics.Probing mechanoregulation of neuronal differentiation by plasma lithography patterned elastomeric substrates.Adaptive reference update (ARU) algorithm. A stochastic search algorithm for efficient optimization of multi-drug cocktailsComputational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancerAn optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells.Rapidly optimizing an aptamer based BoNT sensor by feedback system control (FSC) scheme.Cellular self-organization by autocatalytic alignment feedback.Rapid optimization of drug combinations for the optimal angiostatic treatment of cancerCascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity.A streamlined search technology for identification of synergistic drug combinations.Combination therapy design for maximizing sensitivity and minimizing toxicity.When Medicine Meets Engineering-Paradigm Shifts in Diagnostics and TherapeuticsAn Integrative Pharmacogenomic Approach Identifies Two-drug Combination Therapies for Personalized Cancer Medicine.
P2860
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P2860
Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Closed-loop control of cellula ...... a stochastic search algorithm.
@ast
Closed-loop control of cellula ...... a stochastic search algorithm.
@en
Closed-loop control of cellula ...... a stochastic search algorithm.
@nl
type
label
Closed-loop control of cellula ...... a stochastic search algorithm.
@ast
Closed-loop control of cellula ...... a stochastic search algorithm.
@en
Closed-loop control of cellula ...... a stochastic search algorithm.
@nl
prefLabel
Closed-loop control of cellula ...... a stochastic search algorithm.
@ast
Closed-loop control of cellula ...... a stochastic search algorithm.
@en
Closed-loop control of cellula ...... a stochastic search algorithm.
@nl
P2093
P2860
P356
P1476
Closed-loop control of cellula ...... a stochastic search algorithm.
@en
P2093
Arash Shahangian
Chih-Ming Ho
Pak Kin Wong
P2860
P304
P356
10.1073/PNAS.0800823105
P407
P577
2008-03-20T00:00:00Z