The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
about
Molecular mechanisms of ETS transcription factor-mediated tumorigenesisConserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulatorsA TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcriptionStructure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional TargetsETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formationStructure and Biophysics of CBFβ/RUNX and Its Translocation Products.Understanding single-pass transmembrane receptor signaling from a structural viewpoint-what are we missing?CBFbeta is critical for AML1-ETO and TEL-AML1 activity.Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response.Mtg16/Eto2 contributes to murine T-cell development.RUNX1 mutations in clonal myeloid disorders: from conventional cytogenetics to next generation sequencing, a story 40 years in the makingMyeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence.Retroviral insertions in the VISION database identify molecular pathways in mouse lymphoid leukemia and lymphomaTransforming activity of AML1-ETO is independent of CBFbeta and ETO interaction but requires formation of homo-oligomeric complexes.Differential involvement of E2A-corepressor interactions in distinct leukemogenic pathways.Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesis.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects.Multivalent binding of the ETO corepressor to E proteins facilitates dual repression controls targeting chromatin and the basal transcription machinery.Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.Acute myeloid leukemia with the t(8;21) translocation: clinical consequences and biological implications.A TAF4 coactivator function for E proteins that involves enhanced TFIID binding.CBFA2T3-ZNF652 corepressor complex regulates transcription of the E-box gene HEB.
P2860
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P2860
The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The acute myeloid leukemia fus ...... ociated factor homology domain
@ast
The acute myeloid leukemia fus ...... ociated factor homology domain
@en
The acute myeloid leukemia fus ...... ociated factor homology domain
@nl
type
label
The acute myeloid leukemia fus ...... ociated factor homology domain
@ast
The acute myeloid leukemia fus ...... ociated factor homology domain
@en
The acute myeloid leukemia fus ...... ociated factor homology domain
@nl
prefLabel
The acute myeloid leukemia fus ...... ociated factor homology domain
@ast
The acute myeloid leukemia fus ...... ociated factor homology domain
@en
The acute myeloid leukemia fus ...... ociated factor homology domain
@nl
P2860
P50
P356
P1476
The acute myeloid leukemia fus ...... ociated factor homology domain
@en
P2093
Robert G Roeder
P2860
P304
10242-10247
P356
10.1073/PNAS.0603463103
P407
P577
2006-06-27T00:00:00Z