Hypoxia-inducible regulation of a prodrug-activating enzyme for tumor-specific gene therapy.
about
Transcriptional Targeting in Cancer Gene TherapyGreen fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formationComing of Age in the Life ofHypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization.A novel chimeric promoter that is highly responsive to hypoxia and metals.Tumor-specific gene expression using the survivin promoter is further increased by hypoxiaNovel gene-directed enzyme prodrug therapies against prostate cancer.Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenograftsGene therapy targeting to tumor endothelium.Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo.Gene therapy approaches to enhance bioreductive drug treatment.STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer.Hypoxic tumor microenvironment: Opportunities to develop targeted therapies.Implications of Oxygen Homeostasis for Tumor Biology and Treatment.Hypoxia: A Double-Edged Sword in Cancer Therapy.Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo.Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinase.A tumor-specific gene therapy strategy targeting dysregulation of the VHL/HIF pathway in renal cell carcinomas.A novel adenoviral vector which mediates hypoxia-inducible gene expression selectively in neurons.Development of a hypoxia-inducible cytosine deaminase expression vector for gene-directed prodrug cancer therapy.Hypoxia-inducible tumour-specific promoters as a dual-targeting transcriptional regulation system for cancer gene therapy.Hypoxia-mediated tumour targeting.
P2860
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P2860
Hypoxia-inducible regulation of a prodrug-activating enzyme for tumor-specific gene therapy.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@ast
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@en
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@nl
type
label
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@ast
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@en
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@nl
prefLabel
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@ast
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@en
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@nl
P2093
P2860
P356
P1433
P1476
Hypoxia-inducible regulation o ...... r tumor-specific gene therapy.
@en
P2093
Amato J Giaccia
J Martin Brown
Toru Shibata
P2860
P356
10.1038/SJ.NEO.7900189
P577
2002-01-01T00:00:00Z