Transcription-dependent degradation of topoisomerase I-DNA covalent complexes - Wikidata - awgldk - TriplyDB

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

http://www.wikidata.org/entity/Q34784817

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Processing of damaged DNA ends for double-strand break repair in mammalian cells Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors.Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis.DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1alpha gene locus.Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage.Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents.Transcription blockage by bulky end termini at single-strand breaks in the DNA template: differential effects of 5' and 3' adducts.Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication.Development and validation of an immunoassay for quantification of topoisomerase I in solid tumor tissues Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models.Mycoplasma fermentans inhibits the activity of cellular DNA topoisomerase I by activation of PARP1 and alters the efficacy of its anti-cancer inhibitor Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1.All tangled up: how cells direct, manage and exploit topoisomerase function.Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.Mechanism of heat stress-induced cellular senescence elucidates the exclusive vulnerability of early S-phase cells to mild genotoxic stress.Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.Detection of DNA-protein crosslinks (DPCs) by novel direct fluorescence labeling methods: distinct stabilities of aldehyde and radiation-induced DPCs.Repair of topoisomerase I-mediated DNA damage.ISG15 deregulates autophagy in genotoxin-treated ataxia telangiectasia cells.DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis.CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing.A rapid and sensitive assay for DNA-protein covalent complexes in living cells ISG15 as a novel tumor biomarker for drug sensitivity.Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects.SUMO modification of DNA topoisomerase II: trying to get a CENse of it all Activation of a novel ubiquitin-independent proteasome pathway when RNA polymerase II encounters a protein roadblock.Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.Transcription poisoning by Topoisomerase I is controlled by gene length, splice sites, and miR-142-3p Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks.The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 2: transcriptional regulation Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair.Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts The applications of the novel polymeric fluoropyrimidine F10 in cancer treatment: current evidence.Natural Compounds as Anticancer Agents Targeting DNA Topoisomerases.Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

http://www.wikidata.org/entity/Q34784817

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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MCB.23.7.2341-2350.2003

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Molecular and Cellular Biology

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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Alexandra Rodriguez-Bauman

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Eric H Rubin

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Hui Zhang

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Jin-Ming Yang

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Leroy F Liu

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Murugesan K Gounder

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Shyamal D Desai

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Xiaohua Wu

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P2860

Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells

SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.

A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage.

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies

Effect of prolonged topotecan infusion on topoisomerase 1 levels: a phase I and pharmacodynamic study.

A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin.

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2341-2350

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10853695

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