The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.
about
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosomeAlpha(1A)-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteriesNovel Structural Approaches to Study GPCR RegulationHigh vascular tone of mouse femoral arteries in vivo is determined by sympathetic nerve activity via α1A- and α1D-adrenoceptor subtypesA novel structural framework for α(1A/D)-adrenoceptor selective antagonists identified using subtype selective pharmacophoresThe alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouseAlpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-ARGene deletion of dopamine beta-hydroxylase and alpha1-adrenoceptors demonstrates involvement of catecholamines in vascular remodelingAdrenergic catecholamine trophic activity contributes to flow-mediated arterial remodelingThe zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling.Emerging concepts regarding pannexin 1 in the vasculature.A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.Pannexin 1 in the regulation of vascular tone.Addition of a signal peptide sequence to the alpha1D-adrenoceptor gene increases the density of receptors, as determined by [3H]-prazosin binding in the membranes.Alpha(1D)-adrenergic receptor insensitivity is associated with alterations in its expression and distribution in cultured vascular myocytesAlpha1A/B-knockout mice explain the native alpha1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other alpha1-subtypesThe α₁B -adrenoceptor subtype mediates adrenergic vasoconstriction in mouse retinal arterioles with damaged endothelium.Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors.Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.The α1-adrenergic receptors: diversity of signaling networks and regulationV1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.Alpha-1-adrenergic receptors: targets for agonist drugs to treat heart failure.The vasopressin V1b receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions.Correlation between vasoconstrictor roles and mRNA expression of alpha1-adrenoceptor subtypes in blood vessels of genetically engineered mice.Evidence for involvement of alpha1D-adrenoceptors in contraction of femoral resistance arteries using knockout mice.Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway.Alpha1-adrenoceptors are required for normal male sexual functionOverexpression of Cardiomyocyte α1A-Adrenergic Receptors Attenuates Postinfarct Remodeling by Inducing Angiogenesis Through Heterocellular Signaling.Recent progress in alpha1-adrenergic receptor research.Hypertension, kidney, and transgenics: a fresh perspective.Phospholipase C-delta1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constrictionIdentification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout.Mechanisms Underlying Activation of α₁-Adrenergic Receptor-Induced Trafficking of AQP5 in Rat Parotid Acinar Cells under Isotonic or Hypotonic Conditions.Vascular alpha-1D-adrenoceptors are overexpressed in aorta of the aryl hydrocarbon receptor null mouse: role of increased angiotensin II.{alpha}1-Adrenergic receptor subtypes in nonfailing and failing human myocardiumCardiac alpha1-adrenergic receptors: novel aspects of expression, signaling mechanisms, physiologic function, and clinical importanceThe alpha 1B/D-adrenoceptor knockout mouse permits isolation of the vascular alpha 1A-adrenoceptor and elucidates its relationship to the other subtypes.Altered expression profile of renal α(1D)-adrenergic receptor in diabetes and its modulation by PPAR agonists.Alpha-1-adrenergic receptors in heart failure: the adaptive arm of the cardiac response to chronic catecholamine stimulation.
P2860
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P2860
The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction.
@ast
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction.
@en
type
label
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction.
@ast
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction.
@en
prefLabel
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction.
@ast
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction.
@en
P2093
P2860
P1476
The alpha(1D)-adrenergic recep ...... pressure via vasoconstriction
@en
P2093
Akito Tanoue
Gozoh Tsujimoto
Hitomi Shinoura
Sachie Sunada
Satoshi Takeo
Sayuri Oshikawa
Takayuki Kawai
Yoshihisa Nasa
P2860
P304
P356
10.1172/JCI14001
10.1172/JCI200214001
P407
P577
2002-03-01T00:00:00Z