Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases.
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Lipopolysaccharide-free heat shock protein 60 activates T cellsHsp60-mediated T cell stimulation is independent of TLR4 and IL-12Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophagesCD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patternsUnfolding the Role of Large Heat Shock Proteins: New Insights and Therapeutic ImplicationsFunctions of heat shock proteins in pathways of the innate and adaptive immune systemThe Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer TherapeuticsClients and Oncogenic Roles of Molecular Chaperone gp96/grp94ER chaperones in mammalian development and human diseasesThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityIdentification of gp96 as a novel target for treatment of autoimmune disease in miceThe microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytesA New-Age for Biologic Therapies: Long-Term Drug-Free Therapy with BiP?Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosusCell-surface processing of the metalloprotease pro-ADAMTS9 is influenced by the chaperone GRP94/gp96Degradation of AIMP1/p43 induced by hepatitis C virus E2 leads to upregulation of TGF-β signaling and increase in surface expression of gp96.Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.Detection of novel auto-antigens in patients with recurrent miscarriage: description of an approach and preliminary findings.MyD88 expression is required for efficient cross-presentation of viral antigens from infected cells.Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation.Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells.Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperoneHeat Shock Proteins: Intestinal Gatekeepers that Are Influenced by Dietary Components and the Gut MicrobiotaRole of chaperones and FcgammaR in immunogenic death.Low-variance RNAs identify Parkinson's disease molecular signature in bloodBortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implicationsAngiogenic transforming capacity of IgG purified from plasma of type 1 diabetic patients.Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseasesMolecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity.The heat-shock protein receptors: some answers and more questions.Chaperone gp96-independent inhibition of endotoxin response by chaperone-based peptide inhibitors.Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cellsRole of hsp90 in systemic lupus erythematosus and its clinical relevanceEosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responsesRole of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.The role of glycoprotein 96 in the persistent inflammation of rheumatoid arthritis.Heat shock protein vaccines: from bench to bedside.Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin.Aminoacyl tRNA synthetases and their connections to disease.Pathogen-associated molecular pattern contamination as putative endogenous ligands of Toll-like receptors.
P2860
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P2860
Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Cell surface expression of an ...... systemic autoimmune diseases.
@ast
Cell surface expression of an ...... systemic autoimmune diseases.
@en
Cell surface expression of an ...... systemic autoimmune diseases.
@nl
type
label
Cell surface expression of an ...... systemic autoimmune diseases.
@ast
Cell surface expression of an ...... systemic autoimmune diseases.
@en
Cell surface expression of an ...... systemic autoimmune diseases.
@nl
prefLabel
Cell surface expression of an ...... systemic autoimmune diseases.
@ast
Cell surface expression of an ...... systemic autoimmune diseases.
@en
Cell surface expression of an ...... systemic autoimmune diseases.
@nl
P2093
P2860
P356
P1476
Cell surface expression of an ...... systemic autoimmune diseases.
@en
P2093
P2860
P304
15824-15829
P356
10.1073/PNAS.2635458100
P407
P577
2003-12-10T00:00:00Z