Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe. - Wikidata - awgldk - TriplyDB

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.

http://www.wikidata.org/entity/Q34792326

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Malaria vaccines: identifying Plasmodium falciparum liver-stage targets Plasmodium vivax Controlled Human Malaria Infection - Progress and Prospects The March Toward Malaria Vaccines External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites.Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres.Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines.Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection.Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection.Recent advances in recombinant protein-based malaria vaccines.Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial.Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01 Discriminating Protective from Nonprotective Plasmodium-Specific CD8+ T Cell Responses Current therapies and future possibilities for drug development against liver-stage malaria.Purification of Plasmodium Sporozoites Enhances Parasite-Specific CD8+ T Cell Responses.Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite.Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection.Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines.Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccines Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report.The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8+ T Cells Present in the Liver Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine.Correlates of protective immunity following whole sporozoite vaccination against malaria.The march toward malaria vaccines.Development of whole sporozoite malaria vaccines.The ability to inoculate purified malaria sporozoites will accelerate vaccine and drug discovery.Controlled Human Malaria Infection: Applications, Advances and Challenges.malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication.Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Sporozoite Vaccine in Tanzanian Adults

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Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.

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2013 nî lūn-bûn

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013年の論文

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Alison M Lawrie

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Anusha Gunasekera

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B Kim Lee Sim

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Domtila Kimani

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Eric R James

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Ian D Poulton

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Nicholas A Anagnostou

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Peter F Billingsley

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Rachel Roberts

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Simon Kerridge

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P2860

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

Feeding behaviour and sporozoite ejection by infected Anopheles stephensi

Exoerythrocytic Plasmodium parasites secrete a cysteine protease inhibitor involved in sporozoite invasion and capable of blocking cell death of host hepatocytes

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

Immunization with pre-erythrocytic antigen CelTOS from Plasmodium falciparum elicits cross-species protection against heterologous challenge with Plasmodium berghei

Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins

Cloning and characterization of a novel Plasmodium falciparum sporozoite surface antigen, STARP

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data.

Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection.

Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3

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e65960

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scholarly article

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6

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Adrian V. S. Hill

Andrew R Williams

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Alexander D Douglas

Stephen L Hoffman

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2013-06-18T00:00:00Z

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23823332

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cryopreservation

Plasmodium falciparum

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3688861

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