YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.
about
Discovering gene re-ranking efficiency and conserved gene-gene relationships derived from gene co-expression network analysis on breast cancer data.Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo.Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway.YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB networkA Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines.Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer.Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinomaInhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer CellsDrug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancerDelivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept studySurvivin inhibitor YM155 suppresses gastric cancer xenograft growth in mice without affecting normal tissuesIntegrin α5β1 and p53 convergent pathways in the control of anti-apoptotic proteins PEA-15 and survivin in high-grade gliomaInhibition of long non-coding RNA ROR reverses resistance to Tamoxifen by inducing autophagy in breast cancer.Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer.Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance.Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy.Harnessing Solute Carrier Transporters for Precision Oncology.In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118.Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in Bcl-xL silenced glioma cell lines.YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1.HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells.Survivin as a novel target protein for reducing the proliferation of cancer cells.Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cellslncRNA PCAT6 promotes non-small cell lung cancer cell proliferation, migration and invasion through regulating miR-330-5p
P2860
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P2860
YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
YM155 down-regulates survivin ...... damage in breast cancer cells.
@ast
YM155 down-regulates survivin ...... damage in breast cancer cells.
@en
YM155 down-regulates survivin ...... damage in breast cancer cells.
@nl
type
label
YM155 down-regulates survivin ...... damage in breast cancer cells.
@ast
YM155 down-regulates survivin ...... damage in breast cancer cells.
@en
YM155 down-regulates survivin ...... damage in breast cancer cells.
@nl
prefLabel
YM155 down-regulates survivin ...... damage in breast cancer cells.
@ast
YM155 down-regulates survivin ...... damage in breast cancer cells.
@en
YM155 down-regulates survivin ...... damage in breast cancer cells.
@nl
P2093
P2860
P356
P1476
YM155 down-regulates survivin ...... damage in breast cancer cells.
@en
P2093
C H A Cheung
J R Kanwar
P2860
P304
P356
10.1111/BPH.12935
P407
P577
2014-12-01T00:00:00Z