Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.
about
Novel Investigations of Flavonoids as Chemopreventive Agents for Hepatocellular CarcinomaNK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinomaLack of a 5.9 kDa peptide C-terminal fragment of fibrinogen α chain precedes fibrosis progression in patients with liver disease.The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy.Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemiaWnt16 attenuates TGFβ-induced chondrogenic transformation in vascular smooth muscle.A Small Dibromotyrosine Derivative Purified From Pseudoceratina Sp. Suppresses TGF-β Responsiveness by Inhibiting TGF-β Type I Receptor Serine/Threonine Kinase Activity.Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients.Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis.Galunisertib (LY2157299), a transforming growth factor-β receptor I kinase inhibitor, attenuates acute pancreatitis in rats.Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas.NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-β receptor blocker galunisertib in HCC.Targeting the tumor stroma in hepatocellular carcinoma.Role of IQGAP3 in metastasis and epithelial-mesenchymal transition in human hepatocellular carcinoma.Phase 1 study of galunisertib, a TGF-beta receptor I kinase inhibitor, in Japanese patients with advanced solid tumors.Advances in targeted therapies for hepatocellular carcinoma in the genomic era.Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis.Hook1 inhibits malignancy and epithelial-mesenchymal transition in hepatocellular carcinoma.The rationale for targeting TGF-β in chronic liver diseases.Mucin1 promotes the migration and invasion of hepatocellular carcinoma cells via JNK-mediated phosphorylation of Smad2 at the C-terminal and linker regions.Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathwayTransforming growth factor-β: A therapeutic target for cancer.Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung.Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study.TGFβ Controls Ovarian Cancer Cell ProliferationTGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures.Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies.Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression.Periostin, a signal transduction intermediate in TGF-β-induced EMT in U-87MG human glioblastoma cells, and its inhibition by anthocyanidins.Anti-tumor activity of the TGF-β receptor kinase inhibitor galunisertib (LY2157299 monohydrate) in patient-derived tumor xenografts.Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and HepatocarcinogenesisLY2157299 Monohydrate, a TGF-βR1 Inhibitor, Suppresses Tumor Growth and Ascites Development in Ovarian Cancer
P2860
Q26767372-D07E7A8B-2852-4BF8-A136-7FA37A29C53CQ27001052-88CCC050-D3E1-494F-80A6-87C00399BAF1Q34282455-EDA7C50E-A066-4BFA-B62C-928ECA4503B2Q34599918-4EEF4A25-418C-49E1-BE54-919CDF478056Q34619287-710F50A2-BAD3-4D3B-852B-BE6F0F110EB8Q35130798-CC8C1D5A-2C70-42D4-B075-B4F9AFED20B5Q36010942-4A8B297A-092B-4F81-AD6D-71B3EEE34BE0Q36356409-83155C5C-9BAD-44B0-9785-CA82CD999BBFQ37040720-9C839F24-9670-4277-A904-02B59F683B7BQ37183387-BB75836F-DF20-4FB4-8259-AD51E7DC1D79Q37649636-51D55CFA-3FF7-4D8D-83B5-48C978B88797Q37745263-E3725737-42F7-4656-9328-86A2EDFCF991Q38366586-E1D43A2C-67FC-4743-BD7E-50DB3ACE098CQ38372346-3D4CA26D-0D65-40BE-B28A-3A28D246823BQ38400938-5597C888-0362-43B5-B4DA-E69B6601DEF1Q38521011-95FBC271-C7EE-4A3A-B7C9-E5B0DA30CA6BQ38650120-9D5DD636-FD82-4012-99B9-1D772DDCF060Q38697003-D24B4676-E7E5-417F-B4E8-6837CC1195FEQ38715538-D8D433FB-2637-48F8-80B5-E443F09AB8FDQ38865803-6553A799-181D-4A82-93C0-16FC9812A29BQ38975175-9BAB8DB0-9E60-4EE3-9E66-9547C1EE60F1Q39346505-FDE610A0-704E-4A23-BE67-5F42F515C138Q39626274-79FA5EC3-0888-4392-A379-2EE63C9E9E84Q41084007-5D701095-4D81-41A1-A798-B9466E525716Q41573289-27508AA3-4D56-49C9-8450-FAEBDE067C60Q41617837-34B99852-CA6D-43D2-A64A-8E8D08CFCDA6Q47442360-82A3CFE9-6AF0-465D-9B0A-D66D3FA07486Q52649983-5A827BCB-4401-4243-9362-F6CC08DA81D6Q52668585-833D8D1A-6180-4456-9A98-EDE7A6E9D1A3Q54978821-FB9EFCF4-A3EF-4FF5-924A-0A88EB66D83BQ55068795-997AC360-EBB3-44D0-BFFD-8313B42B11E2Q58754397-27A66448-8114-4126-A09C-F5DF30FB00C3Q58796872-CE64B1C7-15B8-4C18-B2AF-AC9FFE9716E7
P2860
Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@ast
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@en
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@nl
type
label
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@ast
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@en
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@nl
prefLabel
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@ast
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@en
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@nl
P2093
P2860
P50
P1433
P1476
Differential Inhibition of the ...... gainst TGF-β Receptor Type II.
@en
P2093
Angelo Paradiso
Carlo Sabbà
Francesco Dituri
Joan Fernando
Patrizia Papappicco
P2860
P304
P356
10.1371/JOURNAL.PONE.0067109
P407
P577
2013-06-27T00:00:00Z