Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice - Wikidata - awgldk - TriplyDB

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

http://www.wikidata.org/entity/Q34809057

about

Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder Dietary factors, hormesis and health The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies Brain foods: the effects of nutrients on brain function Glutamate and neurotrophic factors in neuronal plasticity and disease Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies Mouse models of polyglutamine diseases: review and data table. Part I Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Role of the hypothalamus in mediating protective effects of dietary restriction during aging Normal huntingtin function: an alternative approach to Huntington's disease SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma 2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease Systemic delivery of recombinant brain derived neurotrophic factor (BDNF) in the R6/2 mouse model of Huntington's disease Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease Energy intake and exercise as determinants of brain health and vulnerability to injury and disease Chronic intermittent fasting improves cognitive functions and brain structures in mice.Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease.Environmental enrichment affects striatal graft morphology and functional recovery.Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease.Perspective: Does brown fat protect against diseases of aging?A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Age and energy intake interact to modify cell stress pathways and stroke outcome.Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington's disease Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle.Recruiting adaptive cellular stress responses for successful brain ageing.The impact of dietary energy intake on cognitive aging.Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines Communication breakdown: the impact of ageing on synapse structure.The Effects of Fasting During Ramadan on the Concentration of Serotonin, Dopamine, Brain-Derived Neurotrophic Factor and Nerve Growth Factor Can the ketogenic diet be anticonvulsant as well as antiepileptogenic?Beneficial effects of environmental enrichment and food entrainment in the R6/2 mouse model of Huntington's disease.Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression Dietary restriction mitigates cocaine-induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior.Neuronutrition and Alzheimer's disease Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity BDNF signaling and survival of striatal neurons.Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats.

P2860

Q21131050-3D615174-4232-473F-8C48-FDC4BE4790C2 Q24626017-ECAF7E24-CDF4-4FFF-8169-0DF47452DCDD Q24644082-54B4C04F-EBB0-4CE0-8D0E-615615E78F75 Q24646616-D95BED76-9709-4B5C-BF5D-A38519BBCF75 Q24647109-D273C20A-AC3D-4A99-8290-21596281C271 Q24653626-9B54066F-DDDE-42F0-87EE-3C1014CEB8FF Q24794955-8F24FD26-7D0D-4E33-9650-1B74AEB76E73 Q26853025-6CF942CD-6287-417F-B88D-ACA0132902D3 Q26864588-222BDF1E-9695-4087-B8FB-3ACE493B2B61 Q27005950-3625385C-D53B-4735-A880-97259794EC92 Q27692402-90E8EDAE-D3C1-4FA8-A4BF-A238AB81AF9F Q28281904-B9399908-408B-4D10-94B4-3C115B403477 Q28301961-714A64D7-ABE1-4BC6-835A-27274B4518F3 Q28478912-09D33F7B-BE07-40D4-ADCF-50BFAB5D0A8D Q28488296-A394CC78-F9C9-495B-8149-DFC04D3DBC72 Q28505492-D5C164BD-AA2C-4D8D-944B-9E205CF9EDE2 Q28710367-A2A2761D-5143-4C70-A7D2-B50486BBFFA8 Q30418840-EA35B53A-FD96-4171-8321-4F7DC78D3A1A Q30846057-230CC7C9-CF40-4126-B57E-64D59972B3B0 Q33197252-C566B339-4378-4CB7-A40E-333EC560B90A Q33327216-5022CACB-D3E4-4C26-839A-44CB0D7C22CC Q33517121-C50F3A5F-C347-40A1-BD59-AEF62C4ECB20 Q33638841-42A5A73F-2FCF-4ECD-98E1-2506AA1F9707 Q33640604-56E9067A-2731-4476-A8DF-750E043980AD Q33750504-42FF99F4-AAF4-4CAD-B9B4-07831CCB925E Q33769984-F02C35F9-BF49-42A6-90D9-A69C534EB5AA Q33817811-22A4DFE0-A645-4AFD-865A-C7E79D38D835 Q33854353-16703DB1-B568-4BDB-B2B9-84945F0718F2 Q33868403-C364F9F8-F98F-4D6E-BBD7-010108B66CAD Q33880898-3C79784A-75FB-4A47-AFF7-CFC8F11D1535 Q33889358-D0F7B1C0-75D3-4DCA-BE0F-AE948D782B9A Q33893484-B93B63F4-FFCE-43E0-BF20-67B0991F711A Q33899396-D54B5DD5-0EB6-47C0-805B-884512404B9A Q33935845-382E0E05-3AD1-45BE-BCA5-0D051CD8D3A1 Q33967163-86D8FDDD-53B5-4422-803E-5126A4D848B3 Q33988290-21C0C24D-AC8B-4163-AC50-AE9392765A1B Q34099466-7F37EF15-44F8-4BAE-84BA-468C577E6216 Q34101256-01DC05AB-08EC-414F-89DE-7391AA3C130D Q34102098-C99F260F-FD4C-4FB1-A8A3-31412064E2BF Q34122843-FE26D4B2-E295-4EC2-95E3-1E754E599206

P2860

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

http://www.wikidata.org/entity/Q34809057

description

2003 nî lūn-bûn

@nan

2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@ast

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@en

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@nl

type

label

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@ast

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@en

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@nl

prefLabel

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@ast

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@en

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@nl

P1433

Q34809057-AA7E8F39-FF32-4C8C-9035-B172A32384FD

P1476

Q34809057-E7BD9832-35F0-4E37-8B00-FF87CEF342F0

P2093

Q34809057-18F3D7DE-4A42-4F94-9991-4AEF10DA12CE

Q34809057-59D848D9-FA8E-49DA-AD46-688AB234C740

Q34809057-7D12B1D5-F267-4C58-A615-38F3CA8E537A

Q34809057-8D52F227-3C03-4B2F-8CDA-250FD89BF57D

Q34809057-A11BC2B3-E461-482B-B2E2-30F7F8548D3C

P2860

Q34809057-05F445EA-4AFE-411A-B593-492F2EC0CE5A

Q34809057-09F1C355-2D83-4FDE-BC2F-FCD4C7BE16BD

Q34809057-17C43309-01E5-4FCB-B2EE-C8C99891D50B

Q34809057-2D972175-3492-41C2-93F3-19C9431E66D3

Q34809057-3D57C247-5ED8-4162-9A2E-F8BEE4C856D8

Q34809057-420B8B80-2F7E-4F69-8F71-F9C61C7AE273

Q34809057-42357ECA-CC0D-459E-A3C9-17B233E1BAAC

Q34809057-4E0ADA3F-3909-4870-8E22-9145A10E5020

Q34809057-542D3D1E-76EB-4709-96C3-E292520A12EF

Q34809057-56DA366B-3882-4B82-8B19-F6AE4A9FFA1D

P304

Q34809057-C7D8EE38-C211-4A13-AA23-8DC102B32B9A

P31

Q34809057-8A696F83-8E1E-4CC9-9667-B208B006C7C3

P356

Q34809057-7B7B76C8-B195-412D-9799-2DC4467314AD

P407

Q34809057-BE9B19FB-BFCC-4C1F-981E-3D5E70B2D0AF

P433

Q34809057-7DA32F07-CB56-4353-8AD8-6BD5C587E559

P478

Q34809057-7F410FB8-B9E7-45CC-9173-80800B6C836E

P50

Q34809057-1FD1AA04-9F26-4410-95C0-540A69B07954

P577

Q34809057-1724CD73-6CBE-40E0-88C8-F81B71991D35

P5875

Q34809057-5FAFC3CA-D5F1-4B83-93DA-5629554ABAAF

P698

Q34809057-4F239FAC-20D0-4A16-89DE-F2AABDE16E6D

P921

Q34809057-7d80dee7-75b5-45bd-8b1f-a5eea2682301

P932

Q34809057-6AAD6FF3-1FF0-4180-974C-456A8718121B

P356

PNAS.0536856100

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Dietary restriction normalizes ...... ival in huntingtin mutant mice

@en

P2093

Haiyang Jiang

http://www.w3.org/2001/XMLSchema#string

Melvin Ware

http://www.w3.org/2001/XMLSchema#string

Wenzhen Duan

http://www.w3.org/2001/XMLSchema#string

Xiao-Jiang Li

http://www.w3.org/2001/XMLSchema#string

Zhihong Guo

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

Accomplices to neuronal death

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes

Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice.

Differential loss of striatal projection neurons in Huntington disease.

P304

2911-2916

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0536856100

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

100

http://www.w3.org/2001/XMLSchema#string

P50

P577

2003-02-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

10898371

http://www.w3.org/2001/XMLSchema#string

P698

12589027

http://www.w3.org/2001/XMLSchema#string

P921

P932

151440

http://www.w3.org/2001/XMLSchema#string