Density functional theory study on a missing piece in understanding of heme chemistry: the reaction mechanism for indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase.
about
The ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamilyMolecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenaseStructure and reaction mechanism in the heme dioxygenases.The mechanism of formation of N-formylkynurenine by heme dioxygenases.Heme enzyme structure and function.Substrate Oxidation by Indoleamine 2,3-Dioxygenase: EVIDENCE FOR A COMMON REACTION MECHANISMO-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1.Exploring the mechanism of tryptophan 2,3-dioxygenaseEvidence for a ferryl intermediate in a heme-based dioxygenase.Molecular basis for the substrate stereoselectivity in tryptophan dioxygenase.Complete reaction mechanism of indoleamine 2,3-dioxygenase as revealed by QM/MM simulations.Theoretical studies of structure, function and reactivity of molecules--a personal account.Tryptophan oxygenation: mechanistic considerations.NADH oxidase activity of indoleamine 2,3-dioxygenase.Heme-containing enzymes and inhibitors for tryptophan metabolism.The first step of the dioxygenation reaction carried out by tryptophan dioxygenase and indoleamine 2,3-dioxygenase as revealed by quantum mechanical/molecular mechanical studiesA short history of heme dioxygenases: rise, fall and rise again.Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopyA dominant homolytic O-Cl bond cleavage with low-spin triplet-state Fe(IV)=O formed is revealed in the mechanism of heme-dependent chlorite dismutase.Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.A theoretical study on oxidative cleavage of olefins to carbonyls catalysed by Fe(iii)-PyBisulidine.
P2860
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P2860
Density functional theory study on a missing piece in understanding of heme chemistry: the reaction mechanism for indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@ast
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@en
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@nl
type
label
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@ast
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@en
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@nl
prefLabel
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@ast
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@en
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@nl
P2093
P356
P1476
Density functional theory stud ...... nd tryptophan 2,3-dioxygenase.
@en
P2093
Hiroshi Sugimoto
Keiji Morokuma
Yoshitsugu Shiro
P304
12299-12309
P356
10.1021/JA803107W
P407
P577
2008-08-20T00:00:00Z