The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.
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Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipaseGPIHBP1 is responsible for the entry of lipoprotein lipase into capillariesGPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guidelineThe Role of Cdkn1A-Interacting Zinc Finger Protein 1 (CIZ1) in DNA Replication and PathophysiologyGlycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 and the intravascular processing of triglyceride-rich lipoproteinsApolipoprotein A-V dependent modulation of plasma triacylglycerol: a puzzlementInfluence of apolipoprotein A-V on the metabolic fate of triacylglycerolGPIHBP1 and lipolysis: an update.Treatment options for hypertriglyceridemia: from risk reduction to pancreatitis.Deletion of the basement membrane heparan sulfate proteoglycan type XVIII collagen causes hypertriglyceridemia in mice and humansGPIHBP1 and the processing of triglyceride-rich lipoproteinsGPIHBP1, an endothelial cell transporter for lipoprotein lipase.Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1.Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cellsEquivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter.Genetic determinants of plasma triglyceridesMutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipaseIdentification and quantitative mRNA analysis of a novel splice variant of GPIHBP1 in dairy cattle.MZF-1/Elk-1 Complex Binds to Protein Kinase Cα Promoter and Is Involved in Hepatocellular Carcinoma.Evidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1).Deletion of GPIHBP1 causing severe chylomicronemiaChylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1New wrinkles in lipoprotein lipase biology.Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells.The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.Biochemistry and pathophysiology of intravascular and intracellular lipolysis.Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia.GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteinsHighly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.The metabolism of triglyceride-rich lipoproteins revisited: new players, new insight.MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cellsThe role of apolipoprotein A5 in obesity and the metabolic syndrome.Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries.GPIHBP1 and Plasma Triglyceride Metabolism.Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation.Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events.
P2860
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P2860
The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@ast
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@en
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@nl
type
label
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@ast
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@en
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@nl
prefLabel
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@ast
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@en
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@nl
P2093
P2860
P356
P1476
The acidic domain of GPIHBP1 i ...... otein lipase and chylomicrons.
@en
P2093
Anne P Beigneux
Brandon S J Davies
Loren G Fong
Michael M Weinstein
Stephen G Young
P2860
P304
29554-29562
P356
10.1074/JBC.M802579200
P407
P577
2008-08-18T00:00:00Z