Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia.
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Challenges in mucosal HIV vaccine development: lessons from non-human primate modelsMucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal ChallengeAntibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trialPhenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model.Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses.Influence of cytokines on HIV-specific antibody-dependent cellular cytotoxicity activation profile of natural killer cells.Improved flow-based method for HIV/SIV envelope-specific memory B-cell evaluation in rhesus macaques.HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaquesReplicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac2HIV infection abrogates the functional advantage of natural killer cells educated through KIR3DL1/HLA-Bw4 interactions to mediate anti-HIV antibody-dependent cellular cytotoxicityReplicating adenovirus-simian immunodeficiency virus (SIV) vectors efficiently prime SIV-specific systemic and mucosal immune responses by targeting myeloid dendritic cells and persisting in rectal macrophages, regardless of immunization route.Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and Are Commonly Detected in Plasma From HIV-infected humansPre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaquesAntibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.Dynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques.Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein.Role of IL-21 and IL-21 receptor on B cells in HIV infection.Cutting edge: novel vaccination modality provides significant protection against mucosal infection by highly pathogenic simian immunodeficiency virusImmunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routesCharacterization of humoral responses to soluble trimeric HIV gp140 from a clade A Ugandan field isolateImpact of antibody quality and anamnestic response on viremia control post-challenge in a combined Tat/Env vaccine regimen in rhesus macaques.Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques.Rhesus macaque rectal and duodenal tissues exhibit B-cell sub-populations distinct from peripheral blood that continuously secrete antigen-specific IgA in short-term explant cultures.Unravelling the mechanisms of durable control of HIV-1.Reduced cell-associated DNA and improved viral control in macaques following passive transfer of a single anti-V2 monoclonal antibody and repeated SHIV challenges.Neutrophil Vaccination Dynamics and Their Capacity To Mediate B Cell Help in Rhesus Macaques
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P2860
Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@ast
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@en
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@nl
type
label
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@ast
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@en
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@nl
prefLabel
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@ast
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@en
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@nl
P2093
P2860
P1433
P1476
Vaccine-elicited SIV and HIV e ...... responses and reduced viremia.
@en
P2093
David Venzon
Egidio Brocca-Cofano
Katherine McKinnon
L Jean Patterson
Mara Daltabuit-Test
Marjorie Robert-Guroff
Rachmat Hidajat
Thorsten Demberg
P2860
P304
P356
10.1016/J.VACCINE.2011.02.066
P407
P577
2011-03-05T00:00:00Z