The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
about
P4-ATPases as Phospholipid Flippases-Structure, Function, and EnigmasOrchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingMammalian P4-ATPases and ABC transporters and their role in phospholipid transportMutations in a P-type ATPase gene cause axonal degenerationThe Essential Neo1 Protein from Budding Yeast Plays a Role in Establishing Aminophospholipid Asymmetry of the Plasma Membrane.Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase.Exposure of phosphatidylserine on the cell surfaceX-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11CP4 ATPases: flippases in health and diseaseZBTB1 is a determinant of lymphoid developmentRole for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migrationMutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infectionATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytesDissecting mammalian immunity through mutation.Mice deficient in the putative phospholipid flippase ATP11C exhibit altered erythrocyte shape, anemia, and reduced erythrocyte life span.Role of flippases, scramblases and transfer proteins in phosphatidylserine subcellular distributionTransport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.Inositol depletion restores vesicle transport in yeast phospholipid flippase mutants.Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases.ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes.Phospholipid flippases: building asymmetric membranes and transport vesicles.A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunityThe Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.Going forward with genetics: recent technological advances and forward genetics in mice.Early events in lymphopoiesis: an update.Type IV P-type ATPases distinguish mono- versus diacyl phosphatidylserine using a cytofacial exit gate in the membrane domain.Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in YeastATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes.After GWAS: mice to the rescue?Loss of Tmem30a leads to photoreceptor degeneration.Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases.Mechanisms of membrane curvature generation in membrane traffic.Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL.Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms.Molecular characterization of a 4,409,480 bp deletion of the human X chromosome in a patient with haemophilia B.Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation.Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.
P2860
Q26741596-14EA5BDC-1890-4BB9-A230-AF9966DD4064Q26862927-76A79138-415B-4D39-A1DF-209A0D7E5DB4Q26866484-3E520AC3-931E-4CA1-A3F6-183DCA5F4047Q27332275-3464936F-A032-4148-8F60-F6CF846FEBB8Q27929973-FEF19551-FB7D-4ED0-B102-92D5136E8484Q27934053-AAF5AAF3-BDFB-49B7-9A06-95BDB8922D44Q28386869-014E6B3E-AF4E-42F6-83D2-7E0E72E493B6Q28388486-4DF70759-AC62-4185-A612-9B323C180572Q28397755-CD6E31AE-BC0A-483F-BCE6-F15F31C45580Q28585897-1EBA7DBF-5A52-45F8-954D-FDA48D385191Q28586745-617E51E2-B827-4EB3-9F53-B299E530CCF0Q28591069-E7D4E068-368E-49A3-86DF-540F6CCFC7DFQ28591671-59AA69F4-B920-4EB1-BB83-2832E109C84DQ33684326-9A654658-AD44-46A7-B1B5-4AA3B9F72131Q33888560-070AF596-9638-48FA-A603-F8A8C78E7BC3Q34441896-EF8F323A-65AB-457E-84BF-A79F0FC933E7Q35192746-13661EA8-5A59-4A0A-A2E0-425D1C613DCDQ35579380-E8FD346E-FD17-4F09-B5BC-0FBBCE3A52ECQ35751047-EBB719C6-CB1E-4AF2-8C05-1AB0F82BBE99Q35901230-512AE96D-57E8-4630-8E12-DAF75309DD01Q36010753-E2B6D056-DF48-4862-AD6D-B0044239321CQ36140212-80F62DA8-16D9-4D26-91D6-964290109420Q36193554-852AEF0F-D9CB-4BE2-B487-D12391AE2407Q36197847-8FCA0672-FC04-48FD-9264-8611C70973B1Q36817566-EBBD0BEA-E70F-48D8-A826-2591CC878F9DQ36912509-66BA6B89-4A5A-4D4B-B0CC-B9330F8434E3Q37000539-B4A6BB49-D6FB-4B3E-A54E-018FD55090F1Q37565720-2C8B781A-C56D-4651-BF27-FFA778CCDB9FQ37606997-5F65BA34-C667-4B1B-ABE0-6F0B9AF736DBQ38048962-E233C6AA-165B-4142-B07F-92A4F64D1F1EQ38609410-53EBA21B-6053-435A-BD23-A49ECEB06A2CQ39410684-F3186F04-0C13-4E48-B047-765FD1925661Q39637109-7984174F-B97A-4848-81A0-2E81CA73203CQ40857983-B43630FF-49B7-45F8-9A1C-D85818C6E549Q42366321-A8EEC4E2-3059-4B1B-8066-95E8D12A7D44Q45862989-B40FEE00-2619-4DC9-BC96-955C410B6EA4Q47171543-A46A3778-72DD-4D91-91F4-8099E22F0B4EQ47689266-009E697E-2EB4-42F6-A161-7EACC2F4AD5AQ48248047-38ABB6E3-8306-41DC-8548-1DEFF76003B6
P2860
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@ast
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@en
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@nl
type
label
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@ast
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@en
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@nl
prefLabel
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@ast
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@en
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@nl
P2093
P2860
P356
P1433
P1476
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
@en
P2093
Carrie N Arnold
Christoph Huber
David Nemazee
Elaine Pirie
P2860
P2888
P304
P356
10.1038/NI.2012
P407
P577
2011-03-20T00:00:00Z
P5875
P6179
1011633428