Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.
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Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck diseaseCytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytesParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsEfficient selenium transfer from mother to offspring in selenoprotein-P-deficient mice enables dose-dependent rescue of phenotypes associated with selenium deficiencyNeuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegenerationEvidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machineryPodocyte specific knock out of selenoproteins does not enhance nephropathy in streptozotocin diabetic C57BL/6 miceSelenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression.Selenoproteins are essential for proper keratinocyte function and skin development.The syndrome of inherited partial SBP2 deficiency in humans.Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.Crucial role of macrophage selenoproteins in experimental colitis.Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified Wybutosine (yW) base in phenylalanine-tRNA.Chlamydomonas reinhardtii selenocysteine tRNA[Ser]Sec.Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis.Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).Selenoprotein expression is essential in endothelial cell development and cardiac muscle functionUnderstanding selenoprotein function and regulation through the use of rodent models.Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development.Loss of housekeeping selenoprotein expression in mouse liver modulates lipoprotein metabolismSelenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis.Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages.A functional link between housekeeping selenoproteins and phase II enzymes.Selenoproteins mediate T cell immunity through an antioxidant mechanism.Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2.Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degenerationNuclease sensitive element binding protein 1 gene disruption results in early embryonic lethalityThe selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice.Molecular mechanisms by which selenoproteins affect cancer risk and progression.Prostate epithelium-specific deletion of the selenocysteine tRNA gene Trsp leads to early onset intraepithelial neoplasia.Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons.Selenoproteins and oxidative stress-induced inflammatory tumorigenesis in the gut.Glutathione contributes to the efflux of selenium from hepatoma cells.Conserved selenoprotein synthesis is not critical for oxidative stress defence and the lifespan of Drosophila.Endogenous and exogenous pathways maintain the reductive capacity of the phagosome.Loss of glutaredoxin 3 impedes mammary lobuloalveolar development during pregnancy and lactation.Selenoproteins in Tumorigenesis and Cancer Progression.Science peels the onion of selenium effects on prostate carcinogenesis.Selenocysteine tRNA[Ser]Sec, the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing.The 811 C/T polymorphism in the 3' untranslated region of the selenoprotein 15-kDa (Sep15) gene and breast cancer in Caucasian women.
P2860
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P2860
Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.
description
2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
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2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Selective removal of the selen ...... ) in mouse mammary epithelium.
@ast
Selective removal of the selen ...... ) in mouse mammary epithelium.
@en
Selective removal of the selenocysteine tRNA [Ser]Sec gene
@nl
type
label
Selective removal of the selen ...... ) in mouse mammary epithelium.
@ast
Selective removal of the selen ...... ) in mouse mammary epithelium.
@en
Selective removal of the selenocysteine tRNA [Ser]Sec gene
@nl
prefLabel
Selective removal of the selen ...... ) in mouse mammary epithelium.
@ast
Selective removal of the selen ...... ) in mouse mammary epithelium.
@en
Selective removal of the selenocysteine tRNA [Ser]Sec gene
@nl
P2093
P2860
P1476
Selective removal of the selen ...... ) in mouse mammary epithelium.
@en
P2093
Bradley A Carlson
Byeong Jae Lee
Dolph L Hatfield
Easwari Kumaraswamy
Eileen Southon
Fanta Morgan
Gertraud W Robinson
Keiko Miyoshi
Lino Tessarollo
P2860
P304
P356
10.1128/MCB.23.5.1477-1488.2003
P407
P577
2003-03-01T00:00:00Z