TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
about
LULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutationTorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeletonMutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystoniaThe AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER proteinBreaching the nuclear envelope in development and diseaseDystonia-associated mutations cause premature degradation of torsinA protein and cell-type-specific mislocalization to the nuclear envelopeA novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear importMutant torsinA interferes with protein processing through the secretory pathway in DYT1 dystonia cells.Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunctionThe nuclear envelope: form and reformation.Inherited isolated dystonia: clinical genetics and gene function.Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons.Primary dystonia: molecules and mechanisms.Nesprin-3: a versatile connector between the nucleus and the cytoskeleton.Diagnostic issues in childhood and adult dystonia.Emerging common molecular pathways for primary dystonia.TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement.This bud's for you: mechanisms of cellular nucleocytoplasmic trafficking via nuclear envelope budding.LINCing defective nuclear-cytoskeletal coupling and DYT1 dystonia.Alternative nuclear transport for cellular protein quality controlTorsinA regulates the LINC to moving nuclei.Effects of genetic variations in the dystonia protein torsinA: identification of polymorphism at residue 216 as protein modifier.
P2860
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P2860
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@ast
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@en
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@nl
type
label
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@ast
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@en
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@nl
prefLabel
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@ast
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@en
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@nl
P2860
P356
P1476
TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope.
@en
P2093
Larry Gerace
P2860
P304
P356
10.1073/PNAS.0402441101
P407
P577
2004-06-08T00:00:00Z