GATA4 deficiency impairs ovarian function in adult mice.

GATA4 deficiency impairs ovarian function in adult mice.

Item
http://www.wikidata.org/entity/Q34827020
Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility.The transcription factor GATA4 is required for follicular development and normal ovarian function.HER2 and GATA4 are new prognostic factors for early-stage ovarian granulosa cell tumor-a long-term follow-up study.GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.Simultaneous gene deletion of gata4 and gata6 leads to early disruption of follicular development and germ cell loss in the murine ovary.GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesisGATA factors in endocrine neoplasiaConditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonatesGATA4 and GATA6 silencing in ovarian granulosa cells affects levels of mRNAs involved in steroidogenesis, extracellular structure organization, IGF-I activity, and apoptosis.FOXL2, GATA4, and SMAD3 co-operatively modulate gene expression, cell viability and apoptosis in ovarian granulosa cell tumor cells.Transcription factors GATA-4 and GATA-6: molecular characterization, expression patterns and possible functions during goose (Anser cygnoides) follicle development.Adiposity Alters Genes Important in Inflammation and Cell Cycle Division in Human Cumulus Granulosa Cell.Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary.
P2860

GATA4 deficiency impairs ovarian function in adult mice.

Item
http://www.wikidata.org/entity/Q34827020
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
GATA4 deficiency impairs ovarian function in adult mice.
@ast
GATA4 deficiency impairs ovarian function in adult mice.
@en
GATA4 deficiency impairs ovarian function in adult mice.
@nl
type
label
GATA4 deficiency impairs ovarian function in adult mice.
@ast
GATA4 deficiency impairs ovarian function in adult mice.
@en
GATA4 deficiency impairs ovarian function in adult mice.
@nl
prefLabel
GATA4 deficiency impairs ovarian function in adult mice.
@ast
GATA4 deficiency impairs ovarian function in adult mice.
@en
GATA4 deficiency impairs ovarian function in adult mice.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
GATA4 deficiency impairs ovarian function in adult mice.
@en
P2093
P2860
P304
P31
P356
10.1095/BIOLREPROD.110.086850
P407
P433
P478
P50
P577
P5875
P698
P932