Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis.
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The Fowler syndrome-associated protein FLVCR2 is an importer of hemeRibosomopathies: how a common root can cause a tree of pathologiesMutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosaDelayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndromeThe Concise Guide to PHARMACOLOGY 2013/14: transporters.Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer.Targeting iron metabolism in drug discovery and deliveryDiamond Blackfan anemia 2008-2009: broadening the scope of ribosome biogenesis disorders.Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells.Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19.Ribosomopathies: mechanisms of disease.Control of intracellular heme levels: heme transporters and heme oxygenasesAnimal models of Diamond Blackfan anemia.Heme and FLVCR-related transporter families SLC48 and SLC49.Genetic predispositions to childhood leukemia.Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme MetabolismMolecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia.Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes.Nonregenerative anemia: mechanisms of decreased or ineffective erythropoiesis.Osteosarcoma: Molecular Pathogenesis and iPSC Modeling.Alteration of heme metabolism in a cellular model of Diamond-Blackfan anemia.Identification of novel subgroup A variants with enhanced receptor binding and replicative capacity in primary isolates of anaemogenic strains of feline leukaemia virus.Identification of a feline leukemia virus variant that can use THTR1, FLVCR1, and FLVCR2 for infection.Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation.FLVCR transports heme from cytosol to extracellular region
P2860
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P2860
Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Enhanced alternative splicing ...... e critical for erythropoiesis.
@ast
Enhanced alternative splicing ...... e critical for erythropoiesis.
@en
Enhanced alternative splicing ...... e critical for erythropoiesis.
@nl
type
label
Enhanced alternative splicing ...... e critical for erythropoiesis.
@ast
Enhanced alternative splicing ...... e critical for erythropoiesis.
@en
Enhanced alternative splicing ...... e critical for erythropoiesis.
@nl
prefLabel
Enhanced alternative splicing ...... e critical for erythropoiesis.
@ast
Enhanced alternative splicing ...... e critical for erythropoiesis.
@en
Enhanced alternative splicing ...... e critical for erythropoiesis.
@nl
P2093
P356
P1433
P1476
Enhanced alternative splicing ...... e critical for erythropoiesis.
@en
P2093
Chetankumar S Tailor
James A Kennedy
Jennifer K Brown
Michelle A Rey
Yigal Dror
P304
P356
10.3324/HAEMATOL.13359
P577
2008-09-24T00:00:00Z