Effect of 17q21 variants and smoking exposure in early-onset asthma.
about
ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6Orm family proteins mediate sphingolipid homeostasisSignal transducer and activator of transcription 6 directly regulates human ORMDL3 expressionDevelopment of biomarkers to optimize pediatric patient management: what makes children different?An understanding of the genetic basis of asthmaA large-scale, consortium-based genomewide association study of asthmaDifferent genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general populationMeta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal studyDevelopment of a High-resolution Melting Analysis Method Based on SYBR Green-I for rs7216389 Locus Genotyping in Asthmatic Child PatientsThe diversity of young adult wheeze: a cluster analysis in a longitudinal birth cohortNetwork-assisted analysis of GWAS data identifies a functionally-relevant gene module for childhood-onset asthma.Toll-like receptor-9 agonist inhibits airway inflammation, remodeling and hyperreactivity in mice exposed to chronic environmental tobacco smoke and allergenGene-environment interactions in asthma and allergy: the end of the beginning?Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiersAssociation of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han populationVariants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosisOrdered subset analysis for case-control studiesAllergic asthma: influence of genetic and environmental factors.Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy.A sequence variant on 17q21 is associated with age at onset and severity of asthma.Age-of-asthma onset as a determinant of different asthma phenotypes in adults: a systematic review and meta-analysis of the literature.Chromosome 17q21 SNP and severe asthma.Greater severity of new onset asthma in allergic subjects who smoke: a 10-year longitudinal studyGenomewide association studies and human disease.Stress and asthma: novel insights on genetic, epigenetic, and immunologic mechanisms.Early life environmental predictors of asthma age-of-onsetMitochondrial Dysfunction and Oxidative Stress in Asthma: Implications for Mitochondria-Targeted Antioxidant TherapeuticsGene-environment interactions in human disease: nuisance or opportunity?Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studiesFrom interaction to co-association --a Fisher r-to-z transformation-based simple statistic for real world genome-wide association studyRisk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locusA polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children.Genomewide association studies in allergy and the influence of ethnicity.Assessing the validity of asthma associations for eight candidate genes and age at diagnosis effectsGenetics of complex airway diseaseThe Association of GSDMB and ORMDL3 Gene Polymorphisms With Asthma: A Meta-AnalysisThe genetics of asthma and allergic disease: a 21st century perspectiveAn ADAM33 polymorphism associates with progression of preschool wheeze into childhood asthma: a prospective case-control study with replication in a birth cohort study.Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes.
P2860
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P2860
Effect of 17q21 variants and smoking exposure in early-onset asthma.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@ast
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@en
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@nl
type
label
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@ast
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@en
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@nl
prefLabel
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@ast
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@en
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@nl
P2093
P50
P356
P1476
Effect of 17q21 variants and smoking exposure in early-onset asthma.
@en
P2093
Anne Boland
Daniel Vervloet
Emmanuelle Bouzigon
Francine Kauffmann
Frédéric Gormand
Hugues Aschard
Isabelle Pin
Jean Bousquet
Jocelyne Just
P304
P356
10.1056/NEJMOA0806604
P407
P577
2008-10-15T00:00:00Z