A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
about
Overexpression of s6 kinase 1 in brain tumours is associated with induction of hypoxia-responsive genes and predicts patients' survivalSignaling by target of rapamycin proteins in cell growth controlOvercoming cisplatin resistance by mTOR inhibitor in lung cancer.Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTORDiacylglycerol Kinases in T Cell Tolerance and Effector FunctionModulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acidMinding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicityQuercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathwaysRapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells.Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signalingPhosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.Predictive value of phosphorylated mammalian target of rapamycin for disease-free survival in breast cancer patients receiving neoadjuvant chemotherapy.The tuberin/mTOR pathway promotes apoptosis of tubular epithelial cells in diabetes.Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis.The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscleAmino acid transporters: roles in amino acid sensing and signalling in animal cells.Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect.The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).Cancer metastasis therapeutic targets and drug discovery: emerging small-molecule protein kinase inhibitors.Hypothalamic leucine metabolism regulates liver glucose production.Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis.Targeting mTOR-mediated survival signals in anticancer therapeutic strategies.Novel treatments for systemic lupus erythematosus.The eIF4E RNA regulon promotes the Akt signaling pathway.PLD1 is overexpressed in an ER-negative MCF-7 cell line variant and a subset of phospho-Akt-negative breast carcinomasA Repertoire of MicroRNAs Regulates Cancer Cell Starvation by Targeting Phospholipase D in a Feedback Loop That Operates Maximally in Cancer CellsPhospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis eventsRegulation of Lipid Signaling by Diacylglycerol Kinases during T Cell Development and FunctionPhosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.Protein kinase inhibitors: contributions from structure to clinical compounds.Lipid second messengers and related enzymes in vertebrate rod outer segments.Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.Intramuscular Anabolic Signaling and Endocrine Response Following Resistance Exercise: Implications for Muscle Hypertrophy.Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-α-Dependent Inhibition of Akt/mTOR Pathway.Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.Characterization of endocytic vesicles using magnetic microbeads coated with signalling ligands.Alternative phospholipase D/mTOR survival signal in human breast cancer cells.Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
P2860
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P2860
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@ast
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@en
A novel pathway regulating the mammalian target of rapamycin
@nl
type
label
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@ast
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@en
A novel pathway regulating the mammalian target of rapamycin
@nl
prefLabel
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@ast
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@en
A novel pathway regulating the mammalian target of rapamycin
@nl
P1476
A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
@en
P2093
P304
P356
10.1016/S0006-2952(02)01263-7
P407
P577
2002-10-01T00:00:00Z