A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity - Wikidata - awgldk - TriplyDB

A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity

A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity

http://www.wikidata.org/entity/Q34876814

about

Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity mTOR Regulation of Lymphoid Cells in Immunity to Pathogens Signaling in T cells - is anything the m(a)TOR with the picture(s)?TCR Signaling in T Cell Memory Integrating canonical and metabolic signalling programmes in the regulation of T cell responses Ways to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytes Signaling by the phosphoinositide 3-kinase family in immune cells Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs PI3K and cancer: lessons, challenges and opportunities New tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeutics Highlights of the advances in basic immunology in 2011.Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection.Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.The battle over mTOR: an emerging theatre in host-pathogen immunity Blockade of mTOR signaling via rapamycin combined with immunotherapy augments antiglioma cytotoxic and memory T-cell functions.mTOR signaling, Tregs and immune modulation.Intersection of mTOR and STAT signaling in immunity mTOR Links Environmental Signals to T Cell Fate Decisions.Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.Resident-Memory CD8 T Cells and mTOR: Generation, Protection, and Clinical Importance.mTOR and metabolic regulation of conventional and regulatory T cells.TOR in the immune system.Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation.A critical role for Rictor in T lymphopoiesis.Regulation and function of mTOR signalling in T cell fate decisions.Immune microenvironment in tumor progression: characteristics and challenges for therapy T cell vaccinology: exploring the known unknowns.CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function.Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation.T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy.Transcriptional regulation of effector and memory CD8+ T cell fates.Phenotype and function of protective, CD4-independent CD8 T cell memory.Regulation of immune responses by mTOR.Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells.Oncolytic virotherapy for renal cell carcinoma: a novel treatment paradigm?Challenges in T cell receptor gene therapy.Homeostasis and the importance for a balance between AKT/mTOR activity and intracellular signaling.

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A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity

http://www.wikidata.org/entity/Q34876814

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

A central role for mTOR kinase ...... cell memory and tumor immunity

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A central role for mTOR kinase ...... cell memory and tumor immunity

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A central role for mTOR kinase ...... cell memory and tumor immunity

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type

label

A central role for mTOR kinase ...... cell memory and tumor immunity

@ast

A central role for mTOR kinase ...... cell memory and tumor immunity

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A central role for mTOR kinase ...... cell memory and tumor immunity

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prefLabel

A central role for mTOR kinase ...... cell memory and tumor immunity

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A central role for mTOR kinase ...... cell memory and tumor immunity

@en

A central role for mTOR kinase ...... cell memory and tumor immunity

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A central role for mTOR kinase ...... cell memory and tumor immunity

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Jonathan D Powell

http://www.w3.org/2001/XMLSchema#string

Koichi Araki

http://www.w3.org/2001/XMLSchema#string

Kristen Pollizzi

http://www.w3.org/2001/XMLSchema#string

Protul A Shrikant

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Qingsheng Li

http://www.w3.org/2001/XMLSchema#string

Rajesh R Rao

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P2860

A novel transcription factor, T-bet, directs Th1 lineage commitment

T cell homeostatic proliferation elicits effective antitumor autoimmunity

mTOR regulates memory CD8 T-cell differentiation

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

The phosphoinositide 3-kinase pathway

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

In vivo cross-presentation of a soluble protein antigen: kinetics, distribution, and generation of effector CTL recognizing dominant and subdominant epitopes.

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

Memory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells.

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