A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity
about
Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunitymTOR Regulation of Lymphoid Cells in Immunity to PathogensSignaling in T cells - is anything the m(a)TOR with the picture(s)?TCR Signaling in T Cell MemoryIntegrating canonical and metabolic signalling programmes in the regulation of T cell responsesWays to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytesSignaling by the phosphoinositide 3-kinase family in immune cellsTsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programsPI3K and cancer: lessons, challenges and opportunitiesNew tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeuticsHighlights of the advances in basic immunology in 2011.Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanomaRole of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection.Modulation of mTOR effector phosphoproteins in blood basophils from allergic patientsMechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.The battle over mTOR: an emerging theatre in host-pathogen immunityBlockade of mTOR signaling via rapamycin combined with immunotherapy augments antiglioma cytotoxic and memory T-cell functions.mTOR signaling, Tregs and immune modulation.Intersection of mTOR and STAT signaling in immunitymTOR Links Environmental Signals to T Cell Fate Decisions.Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.Resident-Memory CD8 T Cells and mTOR: Generation, Protection, and Clinical Importance.mTOR and metabolic regulation of conventional and regulatory T cells.TOR in the immune system.Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation.A critical role for Rictor in T lymphopoiesis.Regulation and function of mTOR signalling in T cell fate decisions.Immune microenvironment in tumor progression: characteristics and challenges for therapyT cell vaccinology: exploring the known unknowns.CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function.Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagyN-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation.T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy.Transcriptional regulation of effector and memory CD8+ T cell fates.Phenotype and function of protective, CD4-independent CD8 T cell memory.Regulation of immune responses by mTOR.Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells.Oncolytic virotherapy for renal cell carcinoma: a novel treatment paradigm?Challenges in T cell receptor gene therapy.Homeostasis and the importance for a balance between AKT/mTOR activity and intracellular signaling.
P2860
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P2860
A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A central role for mTOR kinase ...... cell memory and tumor immunity
@ast
A central role for mTOR kinase ...... cell memory and tumor immunity
@en
A central role for mTOR kinase ...... cell memory and tumor immunity
@nl
type
label
A central role for mTOR kinase ...... cell memory and tumor immunity
@ast
A central role for mTOR kinase ...... cell memory and tumor immunity
@en
A central role for mTOR kinase ...... cell memory and tumor immunity
@nl
prefLabel
A central role for mTOR kinase ...... cell memory and tumor immunity
@ast
A central role for mTOR kinase ...... cell memory and tumor immunity
@en
A central role for mTOR kinase ...... cell memory and tumor immunity
@nl
P2093
P2860
P1433
P1476
A central role for mTOR kinase ...... cell memory and tumor immunity
@en
P2093
Jonathan D Powell
Koichi Araki
Kristen Pollizzi
Protul A Shrikant
Qingsheng Li
Rajesh R Rao
P2860
P304
P356
10.1016/J.IMMUNI.2011.04.006
P407
P50
P577
2011-04-01T00:00:00Z