The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
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Blue-Print Autophagy: Potential for Cancer TreatmentTM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cellsChemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expressionCancer: fundamentals behind pH targeting and the double-edged approachMicroenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy.Nicotine affects bone resorption and suppresses the expression of cathepsin K, MMP-9 and vacuolar-type H(+)-ATPase d2 and actin organization in osteoclasts.Improving the design of the agarose spot assay for eukaryotic cell chemotaxis.Activity of plasma membrane V-ATPases is critical for the invasion of MDA-MB231 breast cancer cells.Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.CERS2 suppresses tumor cell invasion and is associated with decreased V-ATPase and MMP-2/MMP-9 activities in breast cancer.Silencing of TMSG1 enhances metastasis capacity by targeting V-ATPase in breast cancerVacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancerAGPAT9 suppresses cell growth, invasion and metastasis by counteracting acidic tumor microenvironment through KLF4/LASS2/V-ATPase signaling pathway in breast cancerEvidence-based support for the use of proton pump inhibitors in cancer therapyBafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRNA expressionInhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion.Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cellsThe Function of V-ATPases in CancerThe function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer.Recent Insights into the Structure, Regulation, and Function of the V-ATPasesProton Pump Inhibitors Display Antitumor Effects in Barrett's Adenocarcinoma CellsExtracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes.Anti-leukemic effects of the V-ATPase inhibitor Archazolid A.Andrographolide inhibits proliferation of human lung cancer cells and the related mechanisms.The Role of pH Regulation in Cancer Progression.Proton pump inhibitors (PPIs) impact on tumour cell survival, metastatic potential and chemotherapy resistance, and affect expression of resistance-relevant miRNAs in esophageal cancer.Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions.V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo.The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells.Inhibition of the vacuolar ATPase induces Bnip3-dependent death of cancer cells and a reduction in tumor burden and metastasis.The detection of EBP50 expression using quantum dot immunohistochemistry in pancreatic cancer tissue and down-regulated EBP50 effect on PC-2 cells.Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapyEntry of human rhinovirus 89 via ICAM-1 into HeLa epithelial cells is inhibited by actin skeleton disruption and by bafilomycin.Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer.Cleistanthin A inhibits the invasion and metastasis of human melanoma cells by inhibiting the expression of matrix metallopeptidase-2 and -9.Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy.Regulation of endothelial signaling and migration by v-ATPase.
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P2860
The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@ast
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@en
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
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type
label
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@ast
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@en
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@nl
prefLabel
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@ast
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@en
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@nl
P2093
P2860
P356
P1476
The vacuolar-ATPase modulates ...... rms in human pancreatic cancer
@en
P2093
Anthony J Koleske
Christopher C Mader
Chuhan Chung
Fred Gorelick
John C Schmitz
Jorunn Atladottir
Mona L Cornwell
Phillip Fitchev
Susan E Crawford
P2860
P2888
P304
P356
10.1038/LABINVEST.2011.8
P577
2011-02-21T00:00:00Z
P5875
P6179
1047232158