The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells.
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Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingEarly Loss of Splenic Tfh Cells in SIV-Infected Rhesus MacaquesRegulators of Tfh Cell DifferentiationSLy1 regulates T-cell proliferation during Listeria monocytogenes infection in a Foxo1-dependent manner.In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation.ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms.A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells.The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.Follicular Helper T Cells in Autoimmunity.miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.In vivo RNAi screens: concepts and applications.Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cellsThe MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression.CD4 T Follicular Helper Cells and HIV Infection: Friends or Enemies?T follicular helper cell differentiation, function, and roles in disease.The E3 ligase Itch in immune regulation and beyond.T follicular helper cells, T follicular regulatory cells and autoimmunity.T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders.Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function.Insights into the development and regulation of T follicular helper cells.Aberrant Th2 inflammation drives dysfunction of alveolar macrophages and susceptibility to bacterial pneumonia.Signals that drive T follicular helper cell formation.Metabolism in Immune Cell Differentiation and Function.mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.Immune Regulation by Ubiquitin Tagging as Checkpoint Code.Cytoskeletal adaptivity regulates T cell receptor signaling.Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination.The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.Foxo transcription factors in T cell biology and tumor immunity.K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.Regulation of T Follicular Helper Cells in Islet AutoimmunityMolecular Control of Follicular Helper T cell Development and DifferentiationInsights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology
P2860
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P2860
The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@ast
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@en
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@nl
type
label
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@ast
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@en
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@nl
prefLabel
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@ast
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@en
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@nl
P2093
P2860
P356
P1433
P1476
The E3 ubiquitin ligase Itch i ...... of follicular helper T cells.
@en
P2093
Chris Elly
Danelle Eto
Guiying Peng
Nengming Xiao
Shane Crotty
P2860
P2888
P304
P356
10.1038/NI.2912
P407
P50
P577
2014-05-25T00:00:00Z
P5875
P6179
1007707711