TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.
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Reproduction, smell, and neurodevelopmental disorders: genetic defects in different hypogonadotropic hypogonadal syndromesGenetics of isolated hypogonadotropic hypogonadism: role of GnRH receptor and other genesWDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndromeHeparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadismHuman GnRH deficiency: a unique disease model to unravel the ontogeny of GnRH neuronsCongenital Hypogonadotropic Hypogonadism and Kallmann Syndrome: Past, Present, and FutureKisspeptin signalling and its roles in humansComprehensive Review on Kisspeptin and Its Role in Reproductive DisordersAdvances in pubertal growth and factors influencing it: Can we increase pubertal growth?Kisspeptin and the hypothalamic control of reproduction: lessons from the humanCentral hypogonadotropic hypogonadism: genetic complexity of a complex diseaseThe genetic basis of female reproductive disorders: etiology and clinical testingAfferent neuronal control of type-I gonadotropin releasing hormone neurons in the humanEstradiol Membrane-Initiated Signaling and Female ReproductionGPCRs Direct Germline Development and Somatic Gonad Function in PlanariansThe kisspeptin-GnRH pathway in human reproductive health and diseaseMinireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretionInteractions between kisspeptins and neurokinin BThe role of the prokineticin 2 pathway in human reproduction: evidence from the study of human and murine gene mutationsCommentary: the year in endocrine genetics for basic scientistsTwo families with normosmic congenital hypogonadotropic hypogonadism and biallelic mutations in KISS1R (KISS1 receptor): clinical evaluation and molecular characterization of a novel mutationEpigenetic control of female pubertyThe Distribution of Substance P and Kisspeptin in the Mediobasal Hypothalamus of the Male Rhesus Monkey and a Comparison of Intravenous Administration of These Peptides to Release GnRH as Reflected by LH SecretionNeuroendocrine control of the onset of puberty60 YEARS OF NEUROENDOCRINOLOGY: The hypothalamo-pituitary-gonadal axisApplying gene silencing technology to contraceptionThe decline in pulsatile GnRH release, as reflected by circulating LH concentrations, during the infant-juvenile transition in the agonadal male rhesus monkey (Macaca mulatta) is associated with a reduction in kisspeptin content of KNDy neurons of tTargeted gene silencing to induce permanent sterilityNeurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleusHigh-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neuronsAblation of KNDy Neurons Results in Hypogonadotropic Hypogonadism and Amplifies the Steroid-Induced LH Surge in Female Rats.Regulation of gene expression by 17β-estradiol in the arcuate nucleus of the mouse through ERE-dependent and ERE-independent mechanismsNeurokinin B is critical for normal timing of sexual maturation but dispensable for adult reproductive function in female miceDaily successive changes in reproductive gene expression and neuronal activation in the brains of pubertal female mice.Electrophysiology of arcuate neurokinin B neurons in female Tac2-EGFP transgenic mice.Activation of neurokinin 3 receptors stimulates GnRH release in a location-dependent but kisspeptin-independent manner in adult micePrenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in miceArcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight.Leptin is not the critical signal for kisspeptin or luteinising hormone restoration during exit from negative energy balanceUncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men.
P2860
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P2860
TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@ast
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@en
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@nl
type
label
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@ast
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@en
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@nl
prefLabel
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@ast
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@en
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@nl
P2093
P2860
P50
P356
P1433
P1476
TAC3 and TACR3 mutations in fa ...... ntral control of reproduction.
@en
P2093
A Kemal Topaloglu
Ayse Serap Yalin
Ayse Serin
Joshua R Cook
Keith M Porter
L Damla Kotan
Metin Guclu
N Sema Akalin
Neslihan O Mungan
Sazi Imamoglu
P2860
P2888
P304
P356
10.1038/NG.306
P407
P577
2008-12-11T00:00:00Z